Dr Nathan Brendish is a NIHR Clinical Lecturer in Infectious Diseases & General Internal Medicine. His research interests focus on the clinical impact of point-of-care tests for infectious diseases.
Dr Brendish’s expertise in rapid diagnostic tests in severe respiratory virus infection stems from his PhD under Dr Tristan Clark at the University of Southampton. Dr Brendish was the lead study fellow on the ResPOC trial. Dr Brendish continues to be part of Dr Clark’s research group.
The ResPOC trial was a large, pragmatic, randomised controlled trial of routine molecular point-of-care testing for respiratory viruses in adults presenting to hospital with acute respiratory illness versus standard care. This showed that multiplex molecular testing at the point-of-care for respiratory viruses improved diagnosis of influenza, improved appropriate neuraminidase inhibitor prescribing, improved appropriate use of isolation facilities, and decreased length of hospital stay. This seminal study was published in The Lancet Respiratory Medicine in 2017.
Dr Nathan Brendish is a NIHR Clinical Lecturer in Infectious Diseases & General Internal Medicine. His research interests focus on molecular point-of-care testing for infections in hospitalised patients.
Dr Brendish has previously worked as a study physician in the NIHR Southampton Clinical Research Facility on multiple malaria vaccine trials. These studies were often Phase I or Phase II trials, including first-in-human studies and human challenge studies.
- Associate lead for infection teaching for the University of Southampton Medical School.
- Infection Clinical Lecture Series session lead.
- Teaches on the MSc Public Health and MSc Genomic Medicine (Communicable Disease Control module).
Dr Brendish was seconded to Public Health England as a clinical fellow in early 2020 as part of the response to the COVID-19 pandemic.
He was subsequently seconded part-time to the Department of Health and Social Care as a clinical advisor on point-of-care testing, for four months towards the end of 2020.
- BSc, Immunology & Cell Pathology, University College London, 2007
- MBBS, Distinction (top 10%), University College London, 2010
- MRCP, Royal Colleges of Physicians of the UK, 2013
- DMCC, Diploma in the Medical Care of Catastrophes, 2014
- PhD, University of Southampton, 2019