Research project

S Khakoo: Using MHC Class l Peptides to modulate NK cell activity, as a basis for immunotherapy

Lead researchers:

Professor Salim Khakoo
Research funder:

Medical Research Council
Status:

Not active

Staff

Lead researchers

Professor Salim Khakoo

Professor of Hepatology

Connect with Salim

Email: S.I.Khakoo@soton.ac.uk

Research outputs

Constitutive activation of natural killer cells in Primary Biliary Cholangitis

Theresa J. Hydes, Matthew D. Blunt, Jennifer Naftel, Andres F. Vallejo, Grégory Seumois, Alice Wang, Pandurangan Vijayanand, Marta E. Polak & Salim I. Khakoo, 2019, Frontiers in Immunology, 10, 1-12

DOI: 10.3389/fimmu.2019.02633

Type: article

A novel antibody combination to identify KIR2DS2(high) NK cells in KIR2DL3/L2/S2 heterozygous donors

Matthew Blunt, Pauline Rettman, Leidy, Yamile Bastidas Legarda, Rebecca Fulton, Valentino Capizzuto, Mohammed M Naiyer, James A. Traherne & Salim Khakoo, 2019, HLA, 93(1), 32-35

DOI: 10.1111/tan.13413

Type: article

Inhibitory killer cell immunoglobulin-like receptors strengthen CD8⁺ T cell-mediated control of HIV-1, HCV, and HTLV-1

Lies Boelen, Bisrat Debebe, Marcos Silveira, Arafa Salam, Julia Makinde, Chrissy H. Roberts, Eddie C.Y. Wang, John Frater, Jill Gilmour, Katie Twigger, Kristin Ladell, Kelly L. Miners, Jyothi Jayaraman, James A. Traherne, David A. Price, Ying Qi, Maureen P. Martin, Derek C. Macallan, Chloe L. Thio, Jacquie Astemborski, Gregory Kirk, Sharyne M. Donfield, Susan Buchbinder, Salim I. Khakoo, James J. Goedert, John Trowsdale, Mary Carrington, Simon Kollnberger & Becca Asquith, 2018, Science immunology, 3(29)

DOI: 10.1126/sciimmunol.aao2892

Type: article

Activity of IL-12/15/18 primed natural killer cells against hepatocellular carcinoma

Lihui Zhuang, Rebecca J. Fulton, Pauline Rettman, A. Emre Sayan, Jonathan Coad, Aymen Al-Shamkhani & Salim I. Khakoo, 2018, Hepatology International, 1-9

DOI: 10.1007/s12072-018-9909-3

Type: article

Human CD49a+ lung NK cell cytotoxicity in response to Influenza A Virus

Grace, Elizabeth Cooper, Kristoffer Ostridge, Salim I. Khakoo, Tom M.A. Wilkinson & Karl J. Staples, 2018, Frontiers in Immunology, 9

DOI: 10.3389/fimmu.2018.01671

Type: article

Hepatocellular carcinoma

Naveenta Kumar & Salim Khakoo, 2018, HLA

DOI: 10.1111/tan.13275

Type: article

Fine-mapping of genetic loci driving spontaneous clearance of hepatitis C virus infection

Hailiang Huang, Priya Duggal, Chloe L. Thio, Rachel Latanich, James J. Goedert, Alessandra Mangia, Andrea L. Cox, Gregory D. Kirk, Shruti Mehta, Jasneet Aneja, Laurent Alric, Sharyne M. Donfield, Matthew E. Cramp, Salim Khakoo, Leslie H. Tobler, Michael Busch, Graeme J. Alexander, Hugo R. Rosen, Brian R. Edlin, Florencia P. Segal, Georg M. Lauer, David L. Thomas, Mark J. Daly, Raymond T. Chung & Arthur Y. Kim, 2017, Scientific Reports, 7, 1-9

DOI: 10.1038/s41598-017-16011-2

Type: article