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Research project: MACRO - Defining best management for adults with chronic rhinosinusitis

Currently Active:: Yes

Chronic Rhinosinusitis (CRS) is a common condition and symptoms can include a blocked and runny nose, loss of smell, facial pain, tiredness and breathing problems. These symptoms can impact greatly on a person’s quality of life. Patients often consult their GP and may receive a number of different medical treatments including nasal sprays, steroids and antibiotics. Many of these patients will also be referred to an Ear, Nose and Throat (ENT) specialist where they may undergo further medical treatment or sinus surgery, even though the role of surgery in treating CRS is remains unclear.

Project Overview

Aim:

The aim of this study is to understand CRS patients’ views and experiences of living with and being treated for CRS, and to understand GPs and ENT specialist’s views and experiences of treating and managing patient with CRS.

Study Design:

This is a qualitative study consisting of semi structured telephone interviews with adult CRS patients, GPs and ENT specialists. Interviews will be audio-recorded, transcribed and analysed using inductive thematic analysis. The results of this study will be used to inform the wider MACRO programme which is designed to establish best management of patients with CRS.

Local Investigators: Professor Mike Thomas (PI) and Dr Jane Vennik

Funder: NIHR Programme Grants for Applied Research

Duration: October 2016 - 31 May 2023

Contact: Jane Vennik J.Vennik@soton.ac.uk

Related research groups

Primary Care, Population Sciences and Medical Education

Publications

Key Publications

Vennik, J., Eyles, C., Thomas, M., Hopkins, C., Little, P., Blackshaw, H., Schilder, A. G. M., Savage, I., & Philpot, C. (2019). Chronic rhinosinusitis: a qualitative study of patient views and experiences of current management in primary and secondary care. BMJ Open, 9, [e022644]. https://doi.org/10.1136/bmjopen-2018-022644
Philpott, C., Le Conte, S., Beard, D., Cook, J., Sones, W., Morris, S., Clarke, C. S., Thomas, M., Little, P., Vennik, J., Lund, V., Blackshaw, H., Schilder, A., Durham, S., Denaxas, S., Carpenter, J., Boardman, J., Hopkins, C., Med, N., ... Ferreira, T. (2019). Clarithromycin and endoscopic sinus surgery for adults with chronic rhinosinusitis with and without nasal polyps: Study protocol for the MACRO randomised controlled trial. Trials, 20(1), [246]. https://doi.org/10.1186/s13063-019-3314-7
Blackshaw, H., Vennik, J., Philpott, C., Thomas, M., Eyles, C., Carpenter, J., Clarke, C. S., Morris, S., Schilder, A. G. M., Lund, V., Little, P., Durham, S., Denaxas, S., Williamson, E., Beard, D., Cook, J., Le Conte, S., Airey, K., Boardman, J., & Hopkins, C. (2019). Expert panel process to optimise the design of a randomised controlled trial in chronic rhinosinusitis (the MACRO programme). Trials, 20, [230]. https://doi.org/10.1186/s13063-019-3318-3
Vennik, J., Eyles, C., Thomas, D., Hopkins, C., Little, P., Blackshaw, H., Schilder, A. G. M., Boardman, J., & Philpott, C. (2018). Management strategies for chronic rhinosinusitis: A qualitative study of GP and ENT specialist views of current practice in the UK. BMJ Open, 8(12), [e022643]. https://doi.org/10.1136/bmjopen-2018-022643

Staff

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