Publications

Browse our publications catalogue to learn about our research.

Genomic disruption of the histone methyltransferase SETD2 in chronic lymphocytic leukemia

H. Parker, M.J.J. Rose-Zerilli, M. Larrayoz, R. Clifford, J. Edelmann, S. Blakemore, J. Gibson, J. Wang, V. Ljungström, T.K. Wojdacz, T. Chaplin, A. Roghanian, Z. Davis, A. Parker, E. Tausch, S. Ntoufa, S. Ramos, P. Robbe, R. Alsolami, A.J. Steele, G. Packham, A.E. Rodriquez-Vicente, L. Brown, F. McNicholl, F. Forconi, A. Pettitt, P. Hillmen, M. Dyer, M.S. Cragg, C. Chelala, C.C. Oakes, R. Rosenquist, K. Stamatopoulos, S. Stilgenbauer, S. Knight, A. Schuh, D.G. Oscier & J.C. Strefford, 2016, Leukemia, 30(11), 2179–2186

DOI: 10.1038/leu.2016.134

Type: article

The outcome of chronic lymphocytic leukaemia patients with 97% IGHV gene identity to germline is distinct from cases with

Zadie Davis, Francesco Forconi, Anton Parker, Anne Gardiner, Peter Thomas, Daniel Catovsky, Matthew Rose-Zerilli, Jonathan Strefford & David Oscier, 2016, British Journal of Haematology, 1-10

DOI: 10.1111/bjh.13940

Type: article

Engagement of the B-cell receptor of chronic lymphocytic leukemia cells drives global and MYC-specific mRNA translation.

Alison Yeomans, Stephen M. Thirdborough, Beatriz Valle-Argos, Adam Linley, Sergey Krysov, Marina Sanchez Hidalgo, Elodie Leonard, Muhammad Ishfaq, Simon D. Wagner, Anne E. Willis, Andrew Steele, Freda Stevenson, Francesco Forconi, Mark J. Coldwell & Graham Packham, 2016, Blood, 127(4), 449-457

DOI: 10.1182/blood-2015-07-660969

Type: article

The SF3B1 inhibitor spliceostatin A (SSA) elicits apoptosis in chronic lymphocytic leukemia cells through downregulation of Mcl-1

M. Larrayoz, S.J. Blakemore, R.C. Dobson, M.D. Blunt, M.J.J. Rose-Zerilli, R. Walewska, A. Duncombe, D. Oscier, K. Koide, F. Forconi, G. Packham, M. Yoshida, M.S. Cragg, J.C. Strefford & A.J. Steele, 2015, Leukemia, 30, 351-360

DOI: 10.1038/leu.2015.286

Type: article

Genetics and prognostication in splenic marginal zone lymphoma: revelations from deep sequencing

Marina Parry, Matthew J. Rose-Zerilli, Viktor Ljungstrom, Jane Gibson, Jun Wang, Renata Walewska, Helen Parker, A Parker, Zadie David, Anne Gardiner, Neil McIver-Brown, Christina Kalpadakis, Aliki Xochelli, Achilles Anagnostopoulos, Claudia Fazi, David Gonzalez de Castro, Claire Dearden, Guy Pratt, Richard Rosenquist, Margaret Ashton-Key, Francesco Forconi, Andrew R. Collins, Paolo Ghia, Estella Matutes, Gerassimos Pangalis, Kostas Stamatopoulos, David G. Oscier & Jonathan C. Strefford, 2015, Clinical Cancer Research, 21(18), 4174-4183

DOI: 10.1158/1078-0432.CCR-14-2759

Type: article

Perturbation of the normal immune system in patients with CLL

Francesco Forconi & Paul Moss, 2015, Blood, 126(5), 573-581

DOI: 10.1182/blood-2015-03-567388

Type: article

The PI3K/mTOR inhibitor PF-04691502 induces apoptosis and inhibits microenvironmental signaling in CLL and the E?-TCL1 mouse model

Matthew D. Blunt, Matthew J. Carter, Marta Larrayoz, Lindsay D. Smith, Maria Aguilar-Hernandez, Kerry L. Cox, Thomas R.W. Tipton, Mark Reynolds, Sarah Murphy, Elizabeth Lemm, Samantha Dias, Andrew S. Duncombe, Jonathan C. Strefford, Peter W.M. Johnson, Francesco Forconi, Freda K. Stevenson, Graham Packham, Mark S. Cragg & Andrew J. Steele, 2015, Blood, 125(26), 4032-4041

DOI: 10.1182/blood-2014-11-610329

Type: article