Sonya James

Publications

21 publications

Page 1 of 3

FcγRIIB (CD32B) antibodies enhance immune responses through activating FcγRs

Alexander P. Simpson, Robert J. Oldham, Kerry L. Cox, Martin C. Taylor, Sonya James, Yury Bogdanov, Martin J. Glennie, Bjorn Frendeus, Mark S. Cragg & Ali Roghanian, 2025, Clinical and Experimental Immunology, 219(1)

DOI: 10.1093/cei/uxaf015

Type: article

Reducing affinity as a strategy to boost immunomodulatory antibody agonism

Xiaojie Yu, Christian Orr, H.T. Claude Chan, Sonya James, Christine A. Penfold, Jinny Kim, Tatyana Inzhelevskaya, C. Ian Mockridge, Kerry L. Cox, Jonathan W. Essex, Ivo Tews, Martin J. Glennie & Mark Cragg, 2023, Nature, 614(7948), 539-547

DOI: 10.1038/s41586-022-05673-2

Type: article

ATM regulates differentiation of myofibroblastic cancer-associated fibroblasts and can be targeted to overcome immunotherapy resistance

Massimiliano Mellone, Klaudia Piotrowska, VENTURI GIULIA, Lija James, Aleksandra Bzura, Maria-Antoinette Lopez, Sonya James, Chuan Wang, Matthew Ellis, Christopher Hanley, Josephine F. Buckingham, Kerry Cox, Gareth Hughes, Viia Valge-Archer, Emma King, Stephen Beers, Vincent Jaquet, George Jones, Natalia Savelyeva, A. Emre Sayan, Jason Parsons, Stephen Durant & Gareth Thomas, 2022, Cancer Research, 82(24), 4571-4585

DOI: 10.1158/0008-5472.can-22-0435

Type: article

Cyclophosphamide depletes tumor infiltrating T regulatory cells and combined with anti-PD-1 therapy improves survival in murine neuroblastoma

Emily Rose Webb, Julia Moreno Vicente, Alistair Easton, Silvia Lanati, Martin Taylor, Sonya James, Emily L. Williams, Christine Penfold, Stephen Beers, Juliet Gray & Vikki English, 2022, iScience, 25(9)

DOI: 10.1016/j.isci.2022.104995

Type: article

FcγRIIB controls antibody-mediated target cell depletion by ITIM-independent mechanisms

Alexander Patrick Simpson, Ali Roghanian, Robert James Oldham, Claude Chan, Christine Penfold, Sonya James, Yury Bogdanov, Christopher Mockridge, Hyung Kim, Tatyana Inzhelevskaya, Stephen Beers & Mark Cragg, 2022, Cell Reports, 40(3)

DOI: 10.1016/j.celrep.2022.111099

Type: article

HIF activation enhances FcγRIIb expression on mononuclear phagocytes impeding tumor targeting antibody immunotherapy

Khiyam Hussain, Rena Liu, Rosanna C G Smith, Kri T J Müller, Mohammadmersad Ghorbani, Sofia Macari, Kirstie L S Cleary, Robert J Oldham, Russell B Foxall, Sonya James, Steven G Booth, Tom Murray, Lekh N Dahal, Chantal E Hargreaves, Robert S Kemp, Jemma Longley, James Douglas, Hannah Markham, Serena J Chee, Richard J Stopforth, Ali Roghanian, Matthew J Carter, Christian H Ottensmeier, Bjorn Frendéus, Ramsey I Cutress, Ruth R French, Martin J Glennie, Jonathan C Strefford, Stephen M Thirdborough, Stephen A Beers & Mark S Cragg, 2022, Journal of Experimental and Clinical Cancer Research, 41(131), 131

DOI: 10.1186/s13046-022-02294-5

Type: article

On-target IgG hexamerisation driven by a C-terminal IgM tail-piece fusion variant confers augmented complement activation

Joshua M. Sopp, Shirley J. Peters, Tania F. Rowley, Robert J. Oldham, Sonya James, Ian Mockridge, Ruth R. French, Alison Turner, Stephen A. Beers, David P. Humphreys & Mark S. Cragg, 2021, Communications Biology, 4(1)

DOI: 10.1038/s42003-021-02513-3

Type: article

TNF receptor agonists induce distinct receptor clusters to mediate differential agonistic activity

Xiaojie Yu, Sonya James, James H. Felce, Blanka Kellermayer, David A. Johnston, H. T.Claude Chan, Christine A. Penfold, Jinny Kim, Tatyana Inzhelevskaya, C. Ian Mockridge, Yasunori Watanabe, Max Crispin, Ruth R. French, Patrick J. Duriez, Leon R. Douglas, Martin J. Glennie & Mark S. Cragg, 2021, Communications Biology, 4(1), 772

DOI: 10.1038/s42003-021-02309-5

Type: article

Activation of GABA(A) receptors inhibits T cell proliferation

Emma L. Sparrow, Sonya James, Khiyam Hussain, Stephen Beers, Mark Cragg & Yury Bogdanov, 2021, PLoS ONE, 16(5 May)

DOI: 10.1371/journal.pone.0251632

Type: article

Immune characterization of pre-clinical murine models of neuroblastoma

Emily Webb, Silvia Lanati, Carol Wareham, Alistair Easton, Stuart N. Dunn, Tatyana Inzhelevskaya, Freja M. Sadler, Sonya James, Margaret Ashton-Key, Mark Cragg, Stephen Beers & Juliet Gray, 2020, Scientific Reports, 10(1)

DOI: 10.1038/s41598-020-73695-9

Type: article

Dr Sonya James

Connect with Sonya

Publications

Biography

Prizes