Open menu
View all staff
Professor Aymen Al-Shamkhani

Professor Aymen Al-Shamkhani

Professor in Immunology

Research interests

  • Cancer Immunotherapy
  • Immunobiology of costimulatory receptors
  • Immunostimulatory antibodies

More research

Accepting applications from PhD students.

Connect with Aymen

Email: a.al-shamkhani@soton.ac.uk

Address: Southampton General Hospital, Tremona Road Shirley, SO16 6YD (View in Google Maps)

ORCID
Research Publications Supervision External roles and responsibilities Biography

Research

Research groups

Research interests

  • Cancer Immunotherapy
  • Immunobiology of costimulatory receptors
  • Immunostimulatory antibodies
  • Cytotoxic and memory CD8 T cells
  • Mechanisms of tumour immune evasion and resistance to immunotherapy

Research projects

Active projects

Evaluation of the activity and mechanism of action of BT7401
Sponsor: Cancer Research UK
Developing immunostimulatory antibodies to deliver agonism without toxicity
Sponsor: Cancer Research UK
Cancer Research UK Southampton Centre - Non-Clinical Training Award
Sponsor: Cancer Research UK

Completed projects

A Al-Shamkhani phd2004/01 cd20 role
Sponsor: Tenovus
Dr A Al-Shamkhani C1431/A8444
Sponsor: Cancer Research UK
Al-Shamkhani - CRUK - Evaluation of novel therapeutic proteins that combine optimal delivery of T cell costimulatory signals with blockade of immune inhibitory pathways - Aug 15
Sponsor: Cancer Research UK
Shamkhani LLR 12020 Optimising GvL and minimising GvHD
Sponsor: Blood Cancer UK
Prof. A. Al-Shamkhani: Role of TNFRSF25 in GVHD
Sponsor: Blood Cancer UK
Dr A Al-Shamkhani 07-0416
Sponsor: Worldwide Cancer Research
A Al-Shamkhani SA26 CD40 anti tumour
Sponsor: Tenovus
Dr A Al-Shamkhani 07014
Sponsor: Blood Cancer UK
Wellcome Trust Studentship - Aymen Al Sharmkhani
Sponsor: Wellcome Trust
A Al-Shamkhani - Verastem Inc - Combinations of immunostimulatory antibodies and a FAK inhibitor for the treatment of cancer
Sponsor: Verastem Inc
Targeting TNFRSF25 to promote anti-tumour immunity
Sponsor: Cancer Research UK
Prof. Al-Shamkhani: C1431/A13211 Effect of death receptor 3 (TNFRSF25) triggering on effector and regulatory T cells and its impact on the generation of anti-tumour immunity
Sponsor: Cancer Research UK
A Al-Shamkhani 04-026 CD30 signalling
Sponsor: Worldwide Cancer Research
Al-Shamkhani - Celldex - Investigating the effects of CD27 engagement on T cell responses and anti-tumour immunity
Sponsor: Celldex Therapeutics Inc
Al-Shamkhani - Blink Biomedical - Evaluation of anti-CD96 antibodies for cancer immunotherapy (Jan 16)
Sponsor: BLINK BIOMEDICAL SAS
A Al-Shamkhani CRUK C1431/A19502 Monoclonal antibody targeting of TNF receptor superfamily member 25 to promote anti-tumour immunity.
Sponsor: Cancer Research UK
Establishment of a colorectal cancer organoid/peripheral blood mononuclear cell co-culture system to investigate T cell responses in colorectal cancer
Sponsor: Wessex Medical Research
Immune Phenotyping and Repertoire in Colorectal Cancer with Microsatellite Instability
Sponsor: Bowel Disease Research Foundation
Cancer Research UK Southampton Centre - Clinical Training Award
Sponsor: Cancer Research UK
Cancer Research UK Southampton Centre
Sponsor: Cancer Research UK
Centre Core- Senior Lecturer Onc.
Sponsor: Cancer Research UK
Developing Immunomodulatory Monoclonal Antibodies to Promote Cancer Immunity
Prof S Khakoo - NK cell immunotherapy of HCC
Sponsor: British Liver Trust
Prof E. Healy: Dr C. Lai Training fellowship - The role of T cell exhaustion in cutaneous squamous cell carcinoma 100683/Z/12/Z
Sponsor: Wellcome Trust
How to edit profile
Back to top