About
Juliet Gray is a Professor of Paediatric Oncology, working in the Department of Paediatric Oncology at Southampton Children's Hospital and the Centre for Cancer Immunology at the University of Southampton. Her main clinical and research interest is in neuroblastoma and cancer immunotherapy. She leads a translational research group focused on the development of novel antibody therapies, and also leads a number of international clinical trials for children with neuroblastoma.
Research
Research groups
Research interests
- Fc modification of monoclonal antibodies to improve effector function
Research projects
Active projects
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      Sponsor: Childrens Cancer and Leukaemia Group
    
  
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      Sponsor: Cancer Research UK
    
  
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Completed projects
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      Sponsor: Wessex Medical Research
    
  
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      Sponsor: Sparks Children's Medical Research Charity
    
  
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      Sponsor: Cancer Research UK
    
  
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      Sponsor: Wessex Cancer Trust
    
  
      Sponsor: Childrens Cancer and Leukaemia Group
    
  
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      Sponsor: Cancer Research UK
    
  
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      Sponsor: Childrens Cancer and Leukaemia Group
    
  
      Sponsor: Childrens Cancer and Leukaemia Group
    
  
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      Sponsor: Neuroblastoma UK
    
  
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      Sponsor: Cancer Research UK
    
  
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      Sponsor: Cancer Research UK
    
  
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      Sponsor: Children with Cancer UK
    
  
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      Sponsor: Wessex Medical Research
    
  
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      Sponsor: Neuroblastoma UK
    
  
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      Sponsor: Childrens Cancer and Leukaemia Group
    
  
Publications
    60 publications
  
      
      Page 1 of 6
    
  
    
    
    Holger N. Lode, Nikolai  Siebert,  Dominique  Valteau-Couanet & Juliet Gray,    
    2025, Clinical Cancer Research, 31(17), 3692-3701
          
    
    
      Type: article 
    
  
    
    
    Steve Dubois, Lucas Moreno, John Anderson, Juliet Gray & Andrew  Pearson,    
    2025, Pediatric Blood and Cancer, 72(9)
          
        DOI: 10.1002/pbc.31831
      
    
    
      Type: review 
    
  
    
    
    Holger N. Lode, Przemysław  Holko, Aleksandra Wieczorek & Juliet Gray,    
    2025, Cancers, 17(17)
          
    
    
      Type: article 
    
  
    
    
    Hannah L. Smith, Russell B. Foxall, Patrick J. Duriez, Emma L. Teal, Adam D. Hoppe, Janos M. Kanczler, Juliet C. Gray & Stephen A. Beers,    
    2025, The Journal of Immunology, 214(4), 714-725
          
    
    
      Type: article 
    
  
    
    
    Peter J. Gawne, Helen E. Bryant, Steven G.  DuBois, Sally L.  George, Juliet Gray, Leona  Knox, Kyle B.  Matchett, Connie  Peet, Katherine A.  Vallis, Hugh J.  Wallace, Simon  Wan  & Mark N. Gaze,    
    2025, Journal of Nuclear Medicine
    
    
      Type: review 
    
  
    
    
    Lisa Whittaker, Leona  Knox, Connie  Peet, Aine  O'Donovan, Juliet Gray, Simon  Wan, Mark N. Gaze & Glenn Flux,    
    2025, Nuclear Medicine Communications
    
    
      Type: article 
    
  
    
    
    Hannah L. Smith, Stephen A. Beers, Janos M. Kanczler & Juliet C. Gray,    
    2024, The FASEB Journal, 38(24)
          
    
    
      Type: article 
    
  
      Copper chelation redirects neutrophil function to enhance anti-GD2 antibody therapy in neuroblastoma
    
    
    Jourdin R.C.  Rouaen, Antonietta  Salerno, Tyler Shai-Hee, Juliet C. Gray & Orazio Vittorio,    
    2024, Nature Communications, 15
          
    
    
      Type: article 
    
  
    
    
    Katherine M.  Burnand, Jonathan Neville, Annita  Budzanowski, Juliet Gray & Nigel Hall,    
    2024, Pediatric Blood and Cancer, 72(2)
          
        DOI: 10.1002/pbc.31445
      
    
    
      Type: article 
    
  
    
    
    Harrison D. Collier-Bain, Frankie F.  Brown, Adam J. Causer, Lois  Ross, Daniela Rothschild Rodriguez, Noah Browne, Rachel  Eddy, Kirstie L. Cleary, Juliet C. Gray, Mark S. Cragg, Sally Moore, James  Murray, James E.  Turner & John P.  Campbell,    
    2024, Scientific Reports, 14(1)
          
    
    
      Type: article 
    
  Pagination
External roles and responsibilities
        Name:
        Member of Scientific Advisory Board, Solving Kids Cancer (External organisation)
      
      
        Role:
        Member
      
      
        Year:
        2017 - 
      
    
        Name:
        Member of Executive Commitee European Neuroblastom Reseach Network (SIOPEN) (External organisation)
      
      
        Role:
        Member
      
      
        Year:
        2015 - 2019
      
    
        Name:
        Member of NCRI Childhood Cancer Leukaemia Clinical Study Group (External organisation)
      
      
        Role:
        Member
      
      
        Year:
        2017 - 
      
    
        Name:
        Member of CRUK Protocol Safety Review Board  (External organisation)
      
      
        Role:
        Member
      
      
        Year:
        2016 - 
      
    
        Name:
        Invited expert to NICE Single Technology Appraisal Committee (Anti-GD2 in neuroblastoma)  (External organisation)
      
      
        Role:
        Member
      
      
        Year:
        2016 - 2018
      
    
        Name:
        Chair of NCRI CG Neuroblastoma subgroup (External organisation)
      
      
        Role:
        Chair
      
      
        Year:
        2018 - 
      
    
        Name:
        Member of national paediatric Experimental Cancer Medicine Centre Steering Group  (External organisation)
      
      
        Role:
        Member
      
      
        Year:
        2017 - 
      
    
        Name:
        SIOPEN European Neuroblastoma Research Network, Chair of Clinical Trials Committee (External organisation)
      
      
        Role:
        Chair
      
      
        Year:
        2020 - 
      
    
        Name:
        Irish Cancer Society (External organisation)
      
      
        Role:
        Member
      
      
        Year:
        2020
      
    
        Name:
        Neuroblastoma Australia - member of Scientific Advisory Board (External organisation)
      
      
        Role:
        Chair
      
      
        Year:
        2019 - 
      
    Biography
- Early phase immunotherapy trials for neuroblastoma
Prizes
- ‘Outstanding Principal Investigator’ CRN Wessex Awards 2018: (2018)
- Solving Kids Cancer Research Hero (2022)
- ‘Outstanding Principal Investigator’ CRN Wessex Awards 2018: (2018)
- Solving Kids Cancer Research Hero (2022)
