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Engineering and the EnvironmentOur research

Bioengineering Science Research Group

Click here for BESRG twitter
Click here for BESRG twitter

In the Bioengineering Science Research Group, we apply engineering principles to the fields of biology and health care. This covers a diverse range of inter related activities, and in the Bioengineering Group we broadly focus on nutrient transport and absorption in blood vessels and plants, biomechanics of joint replacement patients and amputees,  lab on a chip and sensors for therapeutics and rapid diagnosis and tissue engineering for tissue regeneration and repair. You can find out more about our research by following the links below.

Prof Martin Browne | Head of the Bioengineering Science Research Group

Imaging

Imaging

For More information please click here ...

IMechE CEng
IMechE CEng

IMechE Chartered Engineering (CEng) workshop at the University of Southampton.

We are delighted to announce a forthcoming Chartered Engineering (CEng) workshop, which will be delivered free of charge at the University of Southampton. This is a unique opportunity for all staff and postgraduate students to receive the most relevant and focused help towards becoming a Chartered Engineer with the IMechE.

The workshop is organised with the support of the Bioengineering science research group, the Mechanical Engineering department and the Faculty’s postgraduate office. It will run on two separate days:

Day 1. IMechE CEng workshop: Membership Surgery (CV evaluation) | 21st May 2018 | 10.00 – 15.00 | Room 3011, Building 19, Highfield campus, SO17 1BJ

Registration: First come, first serve. For registration please contact the local organiser. (Contact details below)

All postgraduates and staff are invited to attend a One-2-One consultation (15-minutes) with professional development consultants from the IMechE to evaluate their eligibility for CEng. These consultation sessions will be allocated on a first come first served basis, so please contact the local organiser below if interested. Requirements: Yourself & your CV.

Day 2. IMechE CEng workshop: Training Day | 11th June 2018 | 10.00 – 15.00 | Room 3011, Building 19, Highfield campus, SO17 1BJ

Those selected on the CV evaluation day will be invited to attend a day-long workshop in which a team of professional development consultants from the IMechE will help them complete 70-80% of their application. The requirements for this session will be announced on the membership surgery day.

At the end of the training day, you will be provided information about finishing the application and getting the final support before the submission,

Local organiser: Ali Mosayyebi (a.mosayyebi@soton.ac.uk)

Facilities

Internal Seminars and Conferences

Available Internships

Contact Us

Bioengineering Science Research Facility (Biolab)

Bioengineering science research spans multiple disciplines and this is reflected in the wide range of facilities available for use within the Biolab facility.  The Biolab offers four main suites for tissue testing, cell culture, microscopy and a fully equipped wet laboratory for chemical preparation and the design and fabrication of microfluidic devices. For more information please contact our chief technician Dr Sharon Coleman via bio-lab@soton.ac.uk.

In BESRG, there are two series of seminars to benefit from as follow ...

 

2) Bioengineering PGR | Organised by Dr Rahul S Tare

You can find out more about the 2018 series below ...

Seminar Number1234567
Month Jan Feb Mar Apr May Jun July
Date 24th 28th 28th 25th 23rd 27th 25th
Building/Room  7/3023 5/2011 5/2011 5/2011 7/3021 5/2011 45/2039

 

 

Project 1.

Title | Design and evaluation of a mechanical test rig for mouse bones for research into Paget’s disease

Expected start date | 1st July 2018 for 10 weeks

Project description | This vacation project will form part of a wider interdisciplinary research project into Paget’s disease between Engineering and Biological Sciences in Southampton. Paget’s disease of bone (PDB) is a metabolic bone disease characterised by very high rates of bone remodelling which lead to bone expansion, trabecular disorganisation with a consequent decreases in strength and quality. Macroscopically, the bones are thickened and enlarged with reduced medullary spaces and the marrow is replaced by highly vascularised fibrous tissue. Eventually, bone formation predominates but the osteosclerotic bone is thickened, architecturally disorganised and less able to withstand stress. We are currently characterising a mouse model for the disease, including 3D micro CT/synchrotron imaging and computational modelling of the bone microstructure. While morphological changes have been described previously, actual mechanical testing has never been done before. The aim of this vacation project is to design, realise and test a small 4 point bending rig suitable for mouse bones (femur and tibia). Successful completion of this project will allow us to generate a unique comprehensive data set for these mouse population, including for the first time actual mechanical performance to understand structure-function relationships in Paget’s disease, leading to a high impact publication.

Please contact Dr Philipp Schneider "p.schneider@soton.ac.uk" or Dr Bram Sengers "b.g.sengers@soton.ac.uk" for more details.

 

Project 2.

Title | Impact response of bone

Expected start date | mid June 2018 for 8-10 weeks

Project description | The human body is subjected to dynamic loading in a variety of situations, one of the most common being sporting injuries.  For instance, the average maximum speed for a recreational skier is approximately 30 mph.  More than 20% of all skiing injuries are a broken collar bone that occurs when someone puts out an outstretched hand to break their fall.  However there is limited research on the mechanical response of bone at the high strain rates that would occur from and impact at this speed.  The mechanical properties of bone vary with strain rate, changing both the stiffness and the strength.  The response of bone at low strain rates have been thoroughly studied but, only a limited number of studies have attempted to test the high strain rate response of cortical bone.  Understanding the response of bone at high strain rates is critical for accurately modelling high speed sporting injuries. A student working on this summer project would characterize the mechanical response of bone at 2 strain rates 0.1/s and 1000 1/s in compression.  Quasi-static compression tests will be performed using an eletromechanical test machine.  The high strain rate tests will be performed using a gas gun.  The project will involve preparing bone specimens for testing using a diamond saw and determining the best system for applying a pattern to the samples for strain tracking.  Finally towards the end of the project the student will perform the high and low strain rate compression tests.

Please contact Dr Frances Davis "frances.davis@soton.ac.uk" or Dr Lloyd Fletcher "l.c.fletcher@soton.ac.uk" for more details.

 

Project 3.

Title | Strain rate dependent properties of soft tissues

Expected start date | mid June 2018 for 8-10 weeks

Project description | The human body is subjected to dynamic loading in a variety of situations, one of the most common being sporting injuries.  One of the most serious are the head impacts that occur in sports like American football, boxing, and hockey.  Overtime these repeated impact can cause concussions and in severe cases traumatic brain injuries.  These soft tissue injuries also occur in football where knee ligaments are frequently torn during impacts.  The question is:  How can we protect, rehabilitate, or repair the human body when it is exposed to these impacts?  For instance, the average maximum speed for a recreational skier is approximately 30 mph.  This project will use a drop tower to perform high strain rate tests on skin, ligaments, and tendons to measure how the mechanical properties of the tissues change with strain rate. There is space for two students on this project.  One student will focus is on collecting low strain rate data using existing equipment in the BioLaB.  The second student will focus on the design and build of a custom drop tower for the BioLab.  Both students will come together at the end of the project to run the first series of high strain rate tests using the drop tower.

Please contact Dr Frances Davis "frances.davis@soton.ac.uk" or Dr Lloyd Fletcher "l.c.fletcher@soton.ac.uk" for more details.

 

Stay tuned for more interesting projects ...

Address:

Mechanical Engineering Unit | Engineering and the Environment

Building 5 (Eustice) | University of Southampton

Highfield Campus | Southampton | SO17 1BJ

 

Senior Administrative Officer:

Sue Berger | Tel: +44 (0)23 8059 2871

Administrative Officer:

Katherine Day | Tel: +44 (0)23 8059 2841

Administrative Officer:

Fiona Haigh | Tel: +44 (0)23 8059 7082

Administrative Officer:

Gwyneth Skiller | Tel: +44 (0)23 8059 5568

 

Email:

mecheng@soton.ac.uk

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