Dr Salah Mansour BSc, MSc, PhD
Principal Research Fellow
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Dr Salah Mansour is Principal Research Fellow (Associate Professor) within Medicine at the University of Southampton. He leads a research group that employs a multidisciplinary approach to study the biological functions of CD1 molecules and their “unconventional” lipid reactive T cells. This has broad relevance to human diseases, including tuberculosis, cancer, and autoimmune conditions.
His interest into antigen presentation started with a PhD in molecular Immunology focussing on the MHC class I pathway at Barts Medical School, Queen Mary University of London. After a short stint in industry, he joined Stephan Gadola’s group in Southampton in 2008 as postdoc, before forming his own group in 2013.
His lab combines basic interdisciplinary and translational studies that aim to improve our understanding of CD1 mediated immunity to help develop novel therapeutic targets and diagnostics for patient benefit. Current active funding is from HEFCE, CRUK, MRC, IfLS and PHE.
He has developed strong collaborations with computational and synthetic chemists, structural biologists, and with tuberculosis and cancer clinicians. He also has strong links with Public Health England Porton Down (Dr Sally Sharpe), King’s College London, The Francis Crick Institute, and the Africa Research Institute in Durban.
A greater understanding of CD1 molecules may allow the development of novel diagnostic tests and immunotherapeutic treatments for human diseases including cancer, autoimmunity and tuberculosis infection
Qualifications
BSc (Joint Hons), Biochemistry and Genetics, University of Wales, Swansea (2003).
MSc, Medical Genetics with Immunology, Brunel University (2004)
PhD, Immunology, Barts and the London, Queen Mary University of London (2008)
Appointments held
Principal Research Fellow (Associate Professor), Clinical and Experimental Sciences, University of Southampton 2018-Present
Senior Research Fellow, Clinical and Experimental Sciences, University of Southampton 2013-2018
Research Fellow, Clinical and Experimental Sciences, University of Southampton 2008-2013