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Research project

Salah Mansour: CRUK: A new class of tumour-associated lipid antigens for recognition by CD1c-restriced T Cells

Staff

Lead researcher

Dr Salah Mansour PhD

Associate Professor

Research interests

  • Unconventioanl T cells in health and disease 
  • CD1 group 1 restricted T cell immunity  
  • Structural and molecular mechainsms of CD1 lipid antigen presentation 
Other researchers

Dr Ivo Tews

Associate Professor

Research interests

  • Natural products biosynthesis: a complex cascade of catalytic steps in vitamin B6 biosynthesis is characterised by structures or reaction intermediates in the large PLP syntase complexEdit
  • Bacterial biofilms: understanding of RedOx regulated phosphodiesterase activity in dispersal of biofilms to address chronic infections
  • Cancer immunology: together with Cancer Immunology at Southampton we use a structure based apporach in developing novel cancer therapie

Professor Jonathan Essex

Professor

Professor Bruno Linclau

Professor of Organic Chemistry

Professor Chris Skylaris

Professor of Computational Chemistry

Research interests

  • the computational study of chemical processes, especially in problems involving nanostructures and biological molecules. 

Collaborating research institutes, centres and groups

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