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Research group

Innate Immunity

Coloured microscope image of virus

The Innate Immunity research group conducts interdisciplinary research in the role of innate immune cells in human health and disease.

Part of Medicine


Our investigators are co-located on level E of the South Academic Block at University Hospital Southampton. The group has numerous collaborative projects, and diverse expertise including lymphocyte subsets such as Natural Killer and CD1-responsive T cells, macrophage and fibroblast biology, proteases and bioinformatic/multiomic approaches. Experimental approaches include analysis of patient-derived tissue, advanced cellular modelling, in vivo models and translational studies spanning a range of diseases, including infection, inflammation, wound healing, cancer, metabolic and lung disease.   

People, projects and publications


Miss Grace Bartlett PhD

Senior Research Assistant

Research interests

  • Patient-derived immunotherapeutics
  • Immunopathogenic and inflammatory disease
  • Host immune system-microbiome/tumour microenvironment interactions
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Dr Liku Tezera BM, MSc , PhD

Senior Research Fellow
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Dr Matthew Blunt PhD

Senior Research Fellow

Accepting applications from PhD students

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Dr Michaela Reichmann

Associate Professor Respiratory Medicine

Research interests

  • Integrating bioinformatics and advanced cell culture to understand TB immunopathology and find new host-directed therapeutic targets to treat tuberculosis.

Accepting applications from PhD students

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Professor Paul Elkington

Director of Inst. for Medical Innovation

Research interests

  • tuberculosis
  • immunopathology
  • diagnosis

Accepting applications from PhD students

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Dr Salah Mansour PhD

Associate Professor

Research interests

  • Unconventioanl T cells in health and disease 
  • CD1 group 1 restricted T cell immunity  
  • Structural and molecular mechainsms of CD1 lipid antigen presentation 

Accepting applications from PhD students

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Professor Salim Khakoo

Professor of Hepatology
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Dr Sylvia Pender

Associate Professor
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Professor Tilman Sanchez-Elsner

Professor of Molecular Medicine

Accepting applications from PhD students

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Related research institutes, centres and groups

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