About
Ivo Tews uses crystallography to study molecular interactions. Particular intrests are in large dynamic macromolecular complexes and time resolved techniques. As a member of the CCP4 project for crystallographic software he chairs working group 2, and is engaged in Synchrotron Science at the Diamond Light Source and the EUropean Synchtrotron Radiation Facilty.
Research
Research groups
Member of:
Research interests
- Natural products biosynthesis: a complex cascade of catalytic steps in vitamin B6 biosynthesis is characterised by structures or reaction intermediates in the large PLP syntase complexEdit
- Bacterial biofilms: understanding of RedOx regulated phosphodiesterase activity in dispersal of biofilms to address chronic infections
- Cancer immunology: together with Cancer Immunology at Southampton we use a structure based apporach in developing novel cancer therapie
Research projects
Active projects
Researchers:
Researchers:
Sponsor: Science And Technology Facilities Council
Researchers:
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Sponsor: Medical Research Council
Researchers:
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Researchers:
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Sponsor: Cancer Research UK
Researchers:
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Sponsor: EPSRC
Completed projects
Researchers:
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Sponsor: Cancer Research UK
Researchers:
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Sponsor: Wessex Medical Research
Publications
58 publications
Page 1 of 6
Eugene Krissinel,
& Ivo Tews
, 2022
, Acta Crystallographica Section D: Biological Crystallography
, 78 (9) , 1079--1089
Type: article
Franziska Heckel,
Anna Turaj,
Hayden Fisher,
Michael Marshall,
Christine Penfold,
Tatyana Inzhelevskaya,
Christopher Mockridge,
Diego Alvarado,
Tibor Keler,
& Sean Lim
, 2022
, Communications Biology
, 5 (1) , 1--15
Type: article
Christian M. Orr,
Hayden Fisher,
Xiaojie Yu,
Claude H.T. Chan,
Yunyun Gao,
Steven Booth,
Tatyana Inzhelevskaya,
Christopher Mockridge,
Christine Penfold,
Armin Wagner,
Martin Glennie,
Ann L White,
Arwen R. Pearson,
& Ivo Tews
, 2022
, Science immunology
, 7 (73) , 1--11
Type: article
Tadeo Moreno-Chicano,
Leiah M Carey,
Danny Axford,
John H. Beale,
R. Bruce Doak,
Helen M.E. Duyvesteyn,
Ali Ebrahim,
Robert W Henning,
Diana C.F. Monteiro,
Dean A. Myles,
Shigeki Owada,
Darren Sherrell,
Megan L Straw,
Vukica Srajjer,
Hiroshi Sugimoto,
Kensuke Tono,
Takehiko Tosha,
Ivo Tews,
Martin Trebbin,
Richard W. Strange,
Kelvin L Weiss,
Jonathan A.R. Worrall,
Flora Meilleur,
Robin L. Owen,
Reza A Ghiladi,
& Michael A. Hough
, 2022
, IUCrJ
, 9 (Pt 5) , 610--624
Type: article
Matthew Rodrigues,
Nitai Giri,
Antoine Royant,
Yang Zhang,
Rachel, Ann Bolton,
Gwyndaf Evans,
Steven E. Ealick,
Tadhg P. Begley,
& Ivo Tews
, 2022
, RSC Chemical Biology
, 3 (2) , 227--230
DOI: 10.1039/D1CB00160D
Type: article
Sam Horrell,
Danny Axford,
Nicholas E. Devenish,
Ali Ebrahim,
Michael A. Hough,
Darren A. Sherrell,
Selina L.S. Storm,
Ivo Tews,
Jonathan A.R. Worrall,
& Robin L. Owen
, 2021
, JoVE Journal
, 2021 (168) , 1
DOI: 10.3791/62200
Type: article
Andrew Hutchin,
Charlotte, Rose Cordery,
Martin A. Walsh,
& Ivo Tews
, 2021
, Microbiology Spectrum
, 9 (3)
Type: article
Muchaala Yeboah,
Charys Papagregoriou,
Des C. Jones,
Guangan Hu,
Justine McPartlan,
Christopher Mockridge,
Martin Glennie,
& Ali Roghanian
, 2020
, JCI Insight
, 5 (18)
Type: article
Jeremy Webb,
Dom Bellini,
Andrew Hutchin,
Odel Soren,
& Martin A. Walsh
, 2020
Type: bookChapter
Xiaojie Yu,
H.T. Claude Chan,
Hayden Fisher,
Christine A. Penfold,
Jinny Kim,
Tatyana Inzhelevskaya,
C. Ian Mockridge,
Ruth R. French,
Leon R. Douglas,
Vikki English,
J. Sjef Verbeek,
Ann L White,
Martin J. Glennie,
& Mark S. Cragg
, 2020
, Cancer Cell
, 37 (6) , 850--866.e7
Type: article
Supervision
Current PhD Students
PhD Biological Sciences
Hannah Connabeer
PhD SPITFIRE OES
PhD Biological Sciences
Daniel Mark Burns
PhD Infection Inflamm&Immunity
PhD SoCoBio
PhD Biological Sciences
Yi Wu
PhD Biological Sciences
PhD Chemistry
PhD Chemistry
PhD INSPIRE
Biography
Prizes
- David Blow Prize (2011)
- PD, venia legendi (2011)