About
Ivo Tews uses crystallography to study molecular interactions. Particular intrests are in large dynamic macromolecular complexes and time resolved techniques. As a member of the CCP4 project for crystallographic software he chairs working group 2, and is engaged in Synchrotron Science at the Diamond Light Source and the EUropean Synchtrotron Radiation Facilty.
Research
Research groups
Research interests
- Natural products biosynthesis: a complex cascade of catalytic steps in vitamin B6 biosynthesis is characterised by structures or reaction intermediates in the large PLP syntase complexEdit
- Bacterial biofilms: understanding of RedOx regulated phosphodiesterase activity in dispersal of biofilms to address chronic infections
- Cancer immunology: together with Cancer Immunology at Southampton we use a structure based apporach in developing novel cancer therapie
Research projects
Active projects
Researchers:
Researchers:
Sponsor: Science And Technology Facilities Council
Researchers:
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Sponsor: Medical Research Council
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Researchers:
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Sponsor: Cancer Research UK
Researchers:
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Sponsor: EPSRC
Completed projects
Researchers:
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Researchers:
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Sponsor: Cancer Research UK
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Sponsor: Wessex Medical Research
Publications
61 publications
Page 1 of 7
Xiaojie Yu,
Christian Orr,
H.T. Claude Chan,
Sonya James,
Christine A. Penfold,
Jinny Kim,
Tatyana Inzhelevskaya,
C. Ian Mockridge,
Kerry L. Cox,
Jonathan W. Essex,
Martin J. Glennie,
, 2023
, Nature
, 614 (7948) , 539--547
Type: article
Daniel Burns,
, 2023
, Frontiers in Immunology
, 14
Type: review
Eugene Krissinel,
Andrey A Lebedev,
Ville Uski,
Charles B Ballard,
Ronan M Keegan,
Oleg Kovalevskiy,
Navraj S Pannu,
Pavol Skubák,
John Berrisford,
Maria Fando,
Bernhard Lohkamp,
Marcin Wojdyr,
Adam J Simpkin,
Jens M H Thomas,
Christopher Oliver,
Clemens Vonrhein,
Grzegorz Chojnowski,
Arnaud Basle,
Andrew Purkiss,
Michail N Isupov,
Stuart McNicholas,
Edward Lowe,
Josep Triviño,
Kevin Cowtan,
Jon Agirre,
Daniel J Rigden,
Isabel Uson,
Victor Lamzin,
Ivo Tews,
Gerard Bricogne,
Andrew G W Leslie,
& David G Brown
, 2022
, Acta crystallographica. Section D, Structural biology
, 78 (Pt 9) , 1079--1089
Type: article
Franziska Heckel,
Anna Turaj,
Hayden Fisher,
Michael Marshall,
Osman Dadas,
Christine Penfold,
Tatyana Inzhelevskaya,
Christopher Mockridge,
Diego Alvarado,
Tibor Keler,
Stephen Beers,
& Sean Lim
, 2022
, Communications Biology
, 5 (1) , 1--15
Type: article
Christian M. Orr,
Hayden Fisher,
Xiaojie Yu,
Claude H.T. Chan,
Yunyun Gao,
Steven Booth,
Tatyana Inzhelevskaya,
Christopher Mockridge,
Christine Penfold,
Armin Wagner,
Martin Glennie,
Ann L White,
Arwen R. Pearson,
& Ivo Tews
, 2022
, Science immunology
, 7 (73) , 1--11
Type: article
Tadeo Moreno-Chicano,
Leiah M Carey,
Danny Axford,
John H. Beale,
R. Bruce Doak,
Helen M.E. Duyvesteyn,
Ali Ebrahim,
Robert W Henning,
Diana C.F. Monteiro,
Dean A. Myles,
Shigeki Owada,
Darren Sherrell,
Megan L Straw,
Vukica Srajjer,
Hiroshi Sugimoto,
Kensuke Tono,
Takehiko Tosha,
Martin Trebbin,
Richard W. Strange,
Kelvin L Weiss,
Jonathan A.R. Worrall,
Flora Meilleur,
Robin L. Owen,
Reza A Ghiladi,
& Michael A. Hough
, 2022
, IUCrJ
, 9 (Pt 5) , 610--624
Type: article
Matthew Rodrigues,
Nitai Giri,
Antoine Royant,
Yang Zhang,
Rachel, Ann Bolton,
Gwyndaf Evans,
Steven E. Ealick,
Tadhg P. Begley,
& Ivo Tews
, 2022
, RSC Chemical Biology
, 3 (2) , 227--230
DOI: 10.1039/D1CB00160D
Type: article
Dylan P Ivory,
Ivo Tews,
, 2022
, Nature Communications
, 13 (1)
Type: article
Sam Horrell,
Danny Axford,
Nicholas E. Devenish,
Ali Ebrahim,
Michael A. Hough,
Darren A. Sherrell,
Selina L.S. Storm,
Ivo Tews,
Jonathan A.R. Worrall,
& Robin L. Owen
, 2021
, JoVE Journal
, 2021 (168) , 1
DOI: 10.3791/62200
Type: article
Jeremy Webb,
Andrew Hutchin,
Martin A. Walsh,
& Ivo Tews
, 2021
, Microbiology Spectrum
, 9 (3)
Type: article
Biography
Prizes
- David Blow Prize (2011)
- PD, venia legendi (2011)