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Lay Summaries for all the studies supported by BRAIN UK within the past 12 months. 

Please click on the link below to view the individual lay summary.

BRAIN UK Study Ref Lay SummaryProject Status
 22/001 A study of telomere biology in gliomas and drivers of genomic instability Active
 22/002 ATR drives glioma cell invasion via macropinocytic integrin recycling Active
 22/003 Role of microglial subtypes in neurodevelopmental brain diseases Active
 22/004 Validation of Trimethyl Histone H3 (Lys27) Antibody Active
 22/005 Single-cell transcriptomics of prion diseases Active
 22/006 TDP-43 pathology and loss of function in the skeletal muscle Active
 22/007 Alpha-synuclein pathology in metachromatic leukodystrophy Active
 22/009 Understanding the role of the tumour microenvironment in ependymoma tumours Active
 22/010 3D cerebellar models to predict response to novel combination therapy for medulloblastoma with poor prognosis Active
 22/011 Artificial intelligence-based reconstruction of the WHO 2021 diagnostic algorithm for adult-type diffuse gliomas Active
 22/012 The neuropathological examination of patients administered the AN1792 (Aβ42) vaccine Active
 22/013 The New Roads Team – Innovative approaches to curing Brain Tumours Active
 22/014 Development of a cheap sensitive blood test for early detection of new and proven biomarkers of glioblastoma using fluorescent carbon dots and nanophotonics Active
 22/015 Retrospective and prospective analysis of digital images of histology slides of brain tumours using machine learning and deep learning to predict/identify molecular properties Active
 22/016 Elucidating the Tumour Microenvironment of Primary Central Nervous System Lymphoma Active
 22/017 Microglia activation in IDH1 WT glioma is essential for peripheral macrophage recruitment Active
 22/018 New insight into microglial ageing Active
 22/019 Delving deeper into the appearances and pathophysiological mechanisms of immune checkpoint inhibitor-induced hypophysitis Active
 22/020 Targeting the serine synthesis pathway in central nervous system lymphoma Active
 22/021 Multi-modal computational interrogation of the molecular-morphological intersection in brain tumours Active
 22/022 Investigating spontaneous CAA-related inflammation as a model for Aβ immunotherapy-induced side effects (ARIA) Active
 23/002 Juvenile Dermatomyositis Cohort and Biobank Study Active
 23/003 Investigating the genetic basis of nutritional optic and sensory neuropathy in black African and Caribbean communities in the UK Active


If you are working in a similar area and would like us to try and put you in contact with the Principal Investigator of the study with a view to potential collaboration then please click on the 'suggest collaboration' button below.

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