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The University of Southampton
BRAIN UK

Lay Summaries of studies supported by BRAIN UK by category: Inflammation

 BRAIN UK Study RefLay SummaryProject Status
11/001 Role of neutrophils in the pathogenesis of neuromyelitis optica Closed
11/002 Pilot study comparing microglial markers in different neurological diseases known to be associated with inflammation Active
11/003 Pilot study – Microglia profile in schizophrenia Closed
12/001 Pilot study to identify mast cells and basophils in brain Closed
12/002 Neuropathology of autoimmune/limbic encephalitis associated with antibodies against voltage-gated potassium channels Closed
12/007 Regulation of microglial proliferation and its contribution to chronic neurodegeneration (Lay Summary NOT AVAILABLE) Closed
12/009 Investigation into the impact of systemic inflammation due to infection on microglial phenotype and its contribution to Alzheimer's disease neuropathology Closed
13/002 Investigating inflammation of the normal appearing brain in patients with low-grade glioma Closed
16/003 Activation of the type 1 interferon response by nucleic acids. Active
16/014 Effect of Hypothermia Treatment on Brain inflammation and Development in Neonatal Hypoxic Ischemia Encephalopathy Active
19/018 Somatic mutation in human macrophages: defining ontogeny and mechanisms of inflammatory disease Active
20/007 Investigation of neuropathological changes in COVID-19 Closed
21/015 Neurobiology of inflammation-driven behaviour changes Active
21/023 To understand the pathophysiology of Amyloid-Related Imaging Abnormalities (ARIA) Active
21/024 Entrapment of lipoprotein particles in the brain drives Alzheimer’s disease Active
22/019 Delving deeper into the appearances and pathophysiological mechanisms of immune checkpoint inhibitor-induced hypophysitis Active
23/002 Juvenile Dermatomyositis Cohort and Biobank Study Active
23/011 Clinicopathological correlations of immune response in inflammatory neuropathies Active

 

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