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The University of Southampton

Lay Summaries of studies supported by BRAIN UK by category: Alzheimer's disease.

BRAIN UK Study Ref Lay Summary Project Status
11/007 How do ageing processes contribute to Alzheimer’s disease? Closed
12/009 Investigation into the impact of systemic inflammation due to infection on microglial phenotype and its contribution to Alzheimer's disease neuropathology Closed
13/001 Are neurodegenerative diseases and gliomas inverse comorbidities? Closed
13/010 Pilot study of cholesterol, lipids and LDL in Alzheimer’s disease Active
14/002 Age-modified forms of amyloid-β in a Drosophila model of neurodegeneration and in the brain of Aβ immunised Alzheimer's disease patients Closed
14/003 Studying the role of TUBA8 (tubulin alpha 8) in brain disorders Closed
14/013 Functional characteristics of rare risk variants in TREM2 associated with Alzheimer's disease Active
15/013 Exploratory study: use of MultiOmyx to investigate the pathology of Alzheimer’s disease Closed
16/013 Multi-species biofilm formation in senile plaques in Alzheimer’s disease: Contribution from oral bacteria Closed
20/011 The histopathology underlying Amyloid Related Imaging Abnormalities (ARIA) in Alzheimer’s Disease Closed
20/015 Cellular senescence in brain ageing and AD Closed
21/023 To understand the pathophysiology of Amyloid-Related Imaging Abnormalities (ARIA) Active
21/024 Entrapment of lipoprotein particles in the brain drives Alzheimer’s disease Active
22/012 The neuropathological examination of patients administered the AN1792 (Aβ42) vaccine Active
22/022 Investigating spontaneous CAA-related inflammation as a model for Aβ immunotherapy-induced side effects (ARIA) Active
23/017 AN1792 immunotherapy effects on plaque-associated synapse loss and gliosis Active
23/022 Understanding Porphyromonas gingivalis Infection in Alzheimer’s Disease Active
23/024 The multifaceted role of MMPs and TIMPs in AD after immunotherapy Active


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