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The University of Southampton

Lay Summaries

This section contains lay summaries for all of the projects supported by BRAIN UK. They are grouped by disorder and, for the most recent studies, by year. 

Advice and guidance about how to write a good lay summary for your research project can be found in the formstore.

Image: Arteriovenous malformation


Cerebrovascular diseases are conditions caused by problems that affect the blood supply to the brain, e.g. stroke or subarachnoid haemorrhage.  

Image showing healthy brain vs. diseased brain


Studies which only use tissue with no significant neuropathological abnormality (control tissue). 

Image: Myelin loss in Multiple Sclerosis


A demyelinating disease is any disease of the nervous system in which the myelin sheath of neurons is damaged, e.g. Multiple sclerosis.

Image depicting eplilepsy


Epilepsy is a neurological disorder marked by sudden recurrent episodes of sensory disturbance, loss of consciousness, or convulsions, associated with abnormal electrical activity in the brain.

DNA Strand


A disease or condition caused by an absent or defective gene or by a chromosomal irregularity, e.g. Down's Syndrome.

Image: inflammation


Inflammatory neurological disorders such as encephalitis or meningitis.   

Image: Lewy Body

Neurodegenerative (Other)

A degenerative disease deteriorates the function or structure of tissues or organs, e.g. Huntington's or Parkinson's disease.

Image depicting somebody showing signs of stress


Mental or psychiatric illness refers to a wide range of mental health conditions — disorders that affect your mood, thinking and behaviour, e.g. Schizophrenia or Bipolar disorder.  

Image of brain.


Brain trauma conditions such as Chronic Traumatic Encephalopathy (CTE)

Image: Oligodendroglioma


A tumour is a collection, or mass, of abnormal cells. Tumours can be cancerous (malignant) or non-cancerous (benign).

BRAIN UK Logo Studies Recently Approved
Lay Summaries for all studies approved by BRAIN UK in the past 12 months
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