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Lay Summaries for all the studies supported by BRAIN UK within the past 12 months.

Please click on the link below to view the individual lay summary.

BRAIN UK Study Ref Lay Summary Project Status
23/014 Delineating the neuropathophysiological mechanisms underpinning severe drug-resistant epilepsy in Alpers’ syndrome Active
23/015 Epidemiologic, Histologic, and Molecular Features of Methylation Class Pleomorphic Xanthoastrocytoma Active
23/016 Verifying the surrogate marker, NCOA2, for identifying the HEY1-NCOA2 fusion gene in mesenchymal chondrosarcoma (MCS) Active
23/017 AN1792 immunotherapy effects on plaque-associated synapse loss and gliosis Active
23/018 A Study of Tumours and Embryology of the Meninges and Skull (STEMS) Active
23/019 Mass spectrometry mapping of childhood primary and recurrent cerebellar brain tumours Active
23/020 Investigation the role of Cellular Prion protein (PrP C) in multi drug resistance (MDR) in schwannoma and meningioma tumours Active
23/021 Expression of OxR1 in hypothalamus and pons from normal donors and those with Prader-Willi Syndrome (PWS Active
23/022 Understanding Porphyromonas gingivalis Infection in Alzheimer’s Disease Active
23/023 Understanding microenvironmental determinants of glioblastoma invasion Active
23/024 The multifaceted role of MMPs and TIMPs in AD after immunotherapy Active
23/025 Development of a mass-spectrometry tissue classifier for rapid diagnosis of brain tumours Active
23/026 Genome and transcriptome analysis in DRPLA, other rare repeat expansion disorders and undiagnosed inherited ataxia tissue Active
23/027 Molecular characterisation of novel and rare subtypes of high-grade glioma occurring in the paediatric and young adult age groups Active
24/001 The mosaic brain: a new diagnostic approach in focal epilepsies Active
24/002 Characterization of rare neuronal and glial tumour types to increase diagnostic accuracy, identify treatment targets and improve prognostication Active
24/003 Investigation of corticogenesis defects in Dravet Syndrome patients Active
24/004 P16 expression as a surrogate marker for homozygous deletion of CDKN2A in IDH-mutant astrocytomas Active
24/005 Leveraging Human Cell Atlas technologies to shed light on the immune aetiology of chronic inflammatory demyelinating polyradiculoneuropathy Active

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