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Lay Summaries for all the studies supported by BRAIN UK within the past 12 months. 

Please click on the link below to view the individual lay summary.

BRAIN UK Study Ref Lay SummaryProject Status
 23/001 Investigating the expression of BACE1 in human astrocytoma Active
 23/002 Juvenile Dermatomyositis Cohort and Biobank Study Active
 23/003 Investigating the genetic basis of nutritional optic and sensory neuropathy in black African and Caribbean communities in the UK Active
 23/004 Studying the pathogenesis of Huntington’s disease in post-mortem tissues Active
 23/005 Divergent differentiation in Brain Tumours Active
 23/006 Ascertaining the role of SSTR2 in skull base tumours and brain cancer and potential utility as a diagnostic and/or prognostic biomarker and therapeutic target Active
 23/007 A post-mortem study of progenitor cells and the injury response following severe traumatic brain injury Active
 23/008 Investigation of FGF receptor functions in human glioblastoma Active
 23/009 SPCA in ALS Active
 23/010 The role of amyloid-precursor protein processing (APP) in breast cancer; lessons learnt from Alzheimer’s disease Active
 23/011 Clinicopathological correlations of immune response in inflammatory neuropathies Active
 23/012 Expression of THIKl in temporal cortex from normal donors and those with Temporal Lobe Epilepsy (TLE) Active
 23/014 Delineating the neuropathophysiological mechanisms underpinning severe drug-resistant epilepsy in Alpers’ syndrome Active
 23/015 Epidemiologic, Histologic, and Molecular Features of Methylation Class Pleomorphic Xanthoastrocytoma Active
 23/016 Verifying the surrogate marker, NCOA2, for identifying the HEY1-NCOA2 fusion gene in mesenchymal chondrosarcoma (MCS) Active
 23/017 AN1792 immunotherapy effects on plaque-associated synapse loss and gliosis Active
 23/018 A Study of Tumours and Embryology of the Meninges and Skull (STEMS) Active
 23/019 Mass spectrometry mapping of childhood primary and recurrent cerebellar brain tumours Active
 23/020 Investigation the role of Cellular Prion protein (PrP C) in multi drug resistance (MDR) in schwannoma and meningioma tumours Active
 23/021 Expression of OxR1 in hypothalamus and pons from normal donors and those with Prader-Willi Syndrome (PWS Active
 23/022 Understanding Porphyromonas gingivalis Infection in Alzheimer’s Disease Active
 23/023 Understanding microenvironmental determinants of glioblastoma invasion Active
 23/024 The multifaceted role of MMPs and TIMPs in AD after immunotherapy Active
 23/025 Development of a mass-spectrometry tissue classifier for rapid diagnosis of brain tumours Active
 23/026 Genome and transcriptome analysis in DRPLA, other rare repeat expansion disorders and undiagnosed inherited ataxia tissue  Active
 23/027 Molecular characterisation of novel and rare subtypes of high-grade glioma occurring in the paediatric and young adult age groups Active
 24/001 The mosaic brain: a new diagnostic approach in focal epilepsies Active
24/002 Characterization of rare neuronal and glial tumour types to increase diagnostic accuracy, identify treatment targets and improve prognostication Active

 

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