BIOL3043 Cellular and Molecular Pathology

Module Overview

The module will cover recent advances in selected areas of molecular cell biology, reviewing key aspects of cell and molecular biology required to understand these studies. The application of these studies to the advancement of clinical medicine will also be explored.

Aims and Objectives

Learning Outcomes

Having successfully completed this module you will be able to:

Regulation of epithelial cell-cell adhesion by tumour suppressors and protooncogenes. Dysregulation of this process in invasion and metastasis of cancer cells.
Basic outline of control of the cell cycle and cell metabolism. The role of dysregulation of these processes by genetic and epigenetic changes in the progression and treatment of cancer.
Key aspects of apoptosis and its misregulation in cancers.
Key aspects of the molecular basis of ageing.
understand, describe and discuss the importance of interactions between tumour cells and their microenvironment on cancer development and treatment;
understand, describe and discuss the processes that occur during acute brain injury, and the pathogenesis of acute neurodegeneration
The role of stem cells in normal physiology, and their potential for therapy. The potential of in vitro fertilisation (IVF) and preimplantation genetic diagnosis.

Syllabus

To define recent advances in selected areas of molecular cell biology. To learn aspects of basic cell and molecular biology required to understand these studies To demonstrate how these advances are expanding our knowledge of medical science

Learning and Teaching

Teaching and learning methods

Lectures and independent study.

Type	Hours
Lecture	15
Independent Study	135
Total study time	150

Assessment

Summative

Method	Percentage contribution
Written exam	100%

Referral

Method	Percentage contribution
Written exam	100%

Linked modules

BIOL2002 OR BIOL2010 OR BIOL2011 OR BIOL2014 OR BIOL2022