The University of Southampton
Courses

BIOL6041 Biomedical Technology

Module Overview

This course is designed to illustrate the ways in which the theoretical principles of biochemistry, cellular and molecular biology presented in previous courses can be applied to yield important commercial or therapeutic products or processes.

Aims and Objectives

Module Aims

This course is designed to illustrate the ways in which the theoretical principles of biochemistry, cellular and molecular biology presented in previous courses can be applied to yield important commercial or therapeutic products or processes.

Learning Outcomes

Learning Outcomes

Having successfully completed this module you will be able to:

  • Describe the use of DNA aptamers in biotechnology
  • Explain the methodology used to study genome wide changes in the transcriptome
  • Explain the use of gene cloning to produce recombinant proteins in both prokaryotic and eukaryotic hosts
  • Explain the use of stem cells and their use in medical applications
  • Describe how gene therapy can be used, to treat human disease and how liposomes and viruses can be used to deliver the gene of interest
  • Describe how antibody engineering can be used to treat human disease
  • Describe the use of ScFvs in the design of human monoclonal antibodies
  • Ability to critically aprrasal current methodlogy in Biotechnology

Syllabus

It concentrates on biotechnology that involves prokaryotic and eukaryotic cells. It introduces students to the technologies of the “post genomic” era. It also presents examples of protein engineering, the manipulation of the characteristics of protein molecules such as antibodies and antibody-binding proteins. The course also includes material of the production of therapeutic proteins, the use of gene therapy and stem cells to treat human disease.

Learning and Teaching

Teaching and learning methods

This course comprises i) 20 lectures with 4 feedback/revision seminars. (For each section of the course the student is given a comprehensive reading list of recent research and review papers). ii) A case study documenting the methodology used to produce a therapeutic agent (2000 words) and oral presentation summarising the study . iii) A written 2 hour examination

TypeHours
Independent Study126
Lecture24
Total study time150

Assessment

Assessment Strategy

Written Examination comprising one 2 hour paper requiring two questions to be answered from a choice of four where one is an either/ or (65% of total mark) AND Case study (2000 words) and oral presentation (25% written component, 10% oral) .Re-assessment Method Written Examination comprising one 2 hour paper requiring two questions to be answered from a choice of four where one is an either/ or (65% of total mark) AND Coursework: marks carried forward

Summative

MethodPercentage contribution
Case study  (2000 words) 35%
Written exam  (2 hours) 65%

Referral

MethodPercentage contribution
Case study 35%
Written exam  (2 hours) 65%
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