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The University of Southampton

BIOL6041 Biomedical Technology

Module Overview

This course is designed to illustrate the ways in which the theoretical principles of biochemistry, cellular and molecular biology presented in previous courses can be applied to yield important commercial or therapeutic products or processes.

Aims and Objectives

Learning Outcomes

Learning Outcomes

Having successfully completed this module you will be able to:

  • Describe the use of DNA as molecule for detecting small molecules, nucleic acids and proteins.
  • Explain the use of gene cloning to produce recombinant proteins in both prokaryotic and eukaryotic hosts.
  • Explain the use of stem cells and their use in medical applications
  • Describe how gene therapy can be used, to treat human disease and how liposomes and viruses can be used to deliver the gene of interest
  • Describe how antibody engineering can be used to treat human disease
  • Describe the use of ScFvs in the design of human monoclonal antibodies
  • Describe how pre-clinical models are used to test potential new therapies.
  • Critically appraise current methodology in Biotechnology


This module concentrates on biotechnology that involves prokaryotic and eukaryotic cells. It introduces students to the technologies of the “post genomic” era. It also presents examples of protein engineering, the manipulation of the characteristics of protein molecules such as antibodies and antibody-binding proteins. The course also includes material on the production of therapeutic proteins, the use of gene therapy and stem cells to treat human disease, and the pre-clinical models required to test them.

Learning and Teaching

Teaching and learning methods

This course comprises: i) 20 lectures with 2 feedback/revision seminars. (For each section of the course the student is given a comprehensive reading list of recent research and review papers). ii) A conference abstract (350 words) and poster documenting a case study of the methodology used to produce a therapeutic agent. iii) A written 2 hour examination.

Independent Study126
Total study time150



MethodPercentage contribution
Case study  (2000 words) 25%
Written assessment 75%


MethodPercentage contribution
Case study 25%
Written assessment  (2 hours) 75%

Repeat Information

Repeat type: Internal & External

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