Pre-requisites: CHEM3038 or CHEM6095
Aims and Objectives
Having successfully completed this module you will be able to:
- Discuss the mode of action of important classes of chemical probes.
- Understand the importance of chemical biology methods for the discovery of novel drugs to treat diseases.
- Describe essential techniques employed in chemical biology for the synthesis, characterisation and engineering of biomolecules.
- Draw the structure of common biorthogonal reagents and the molecular mechanisms (curly arrows) underlying protein labelling.
- Highlight key applications of synthetic methods to understanding the biological function of carbohydrate based biomolecules.
- Proteins, nucleic acids and their characterisation
- Protein engineering, directed evolution and synthetic biologicals
- Chemical probes to study biomolecules: design and mode of action
- Bioconjugation reactions and labelling of peptides and proteins
- Understanding glycobiology with chemistry
Learning and Teaching
Teaching and learning methods
|Wider reading or practice||44|
|Preparation for scheduled sessions||6|
|Total study time||124|
This is how we’ll formally assess what you have learned in this module.
Repeat type: Internal & External