The University of Southampton
Courses

MEDI6223 Stem Cells, Development & Regenerative Medicine Short Title: Stem Cells, Devlpmnt & Reg Med

Module Overview

The module consists of ten sessions covering the following topics: i) Embryonic stem cells ii) Neural stem cells iii) Musculoskeletal stem cells iv) Cancer stem cells v) Ethics Topics 1, 3 and 5 will consist of an additional 2 hour session, each session one week apart. Each topic will be taught by an academic with a specialist interest in the subject area. The sessions will combine a seminar and general discussion in order to clarify any points and to frame any questions arising from the lecture that the students find interesting. Prior to each topic, the relevant manuscript and supporting documentation will be uploaded onto the course materials section of Blackboard. You should read the methods section, in order to ensure that you are familiar with the basic principles of the techniques and/or any confusing abbreviations used. Methodological queries will be discussed at the session. For topics 1, 3 and 5, one or more students, depending on class numbers will be designated to prepare an oral presentation on the paper for the following week. This will comprise the paper and background questions arising from the article or the seminar. All students will be expected to join in the discussion of the paper during and after the presentation, although only presenting students will be graded. Presenting students will be expected to research other articles to introduce concepts in the paper. All students will be expected to research other articles to bring to the general discussion of paper. For topics 2 and 4, all students will write a review of the paper stating the hypothesis and summarising the background, results and conclusions with comment on strengths, weaknesses and any new questions arising as a consequence of the paper. There will be no oral presentation for these topics.

Aims and Objectives

Module Aims

The aims of the module are: • To provide you with an understanding of stem cell biology and its application for regenerative medicine. • To develop your skills in critical appraisal of previously published research. • To enhance your oral skills required for the presentation and interpretation of data

Learning Outcomes

Knowledge and Understanding

Having successfully completed this module, you will be able to demonstrate knowledge and understanding of:

  • Define characteristics of different types of stem cells. (Programme LO A5)
  • Identify the application and translational potential of stem cells (Programme LO A5)
  • Understand important principles and techniques relating to stem cell experimentation. (Programme LO A2)
  • Appreciate the ethical issues associated with use of stem cells. (Programme LO A3)
Cognitive Skills

Having successfully completed this module you will be able to:

  • Understand and summarise stem cell work carried out by others in specific fields of research. (Programme LO A4, B1)
  • Apply information identified from published sources to your own investigations. (Programme LO A4, B1, C3)
Transferable and Generic Skills

Having successfully completed this module you will be able to:

  • Organise your own activities to achieve a desired outcome within a limited amount of time. (Programme LO B5, C1)
  • Direct your own learning. (Programme LO C2)
  • Exercise initiative and personal responsibility. (Programme LO D1)
Learning Outcomes

Having successfully completed this module you will be able to:

  • Give succinct oral presentations and discuss the importance and relevance of published work (Programme LO B6, B7, C4, C6)
  • Produce a concise written summary and appraisal of published work including an assessment of its importance in the field of study. (Programme LO B6, B7, C7)

Syllabus

Weeks 1 & 2: • Human embryonic stem cells Weeks 3: • Neural stem cells Weeks 5 & 6: • Musculoskeletal stem cells Weeks 7: • Cancer stem cells Weeks 9-10: • Ethics

Learning and Teaching

Teaching and learning methods

A variety of methods will be used including seminars, group discussions, journal club presentations all of which incorporate the evaluation and presentation of research findings within the field of stem cell biology. Total Study Time The module will reflect the normal distribution of 200 hours of student effort attributable to this 20 credit module. Contact hours: 16 Non-contact hours: 184

TypeHours
Teaching16
Independent Study184
Total study time200

Resources & Reading list

Current review articles and primary research papers will be accessible through the University of Southampton electronic journals collection.. 

Assessment

Assessment Strategy

The assessment for the module provides you with the opportunity to demonstrate achievement of the learning outcomes. There will be two parts to the assessment, one based on oral presentation skills and the other on the written presentation skills required to review and critically appraise the work of other researchers in the field of study. The incorporation and demonstration of an understanding of stem cell biology will also be important in developing the research proposal produced during the Research Skills for Biomedical Sciences module. The markers/reviewers will be staff associated with the module. All assignments will be double marked, and an agreed mark provided. Assessed Course Work: 1) Presentation and discussion of a chosen paper at Journal Club (30%) 2) A concise written review (maximum 1000 words) of two nominated research articles incorporating a critical assessment of data quality and experimental strategy in the relevant field of research. Each review will contribute 35% to the final mark (Total 70%). Assessment requirements You must pass the module overall at 50% or above. All elements must be passed, no compensation allowed. Candidates who fail the module at the first attempt will be permitted to re-sit specific elements as supplementary assessments as agreed by the module lead. Candidates who achieve at least 50% overall at the second attempt will be permitted to pass the module and the module mark will be capped at 50%

Summative

MethodPercentage contribution
Oral presentation 30%
Written review  (1000 words) 35%
Written review  (1000 words) 35%

Referral

MethodPercentage contribution
Oral presentation 30%
Written review  (1000 words) 35%
Written review  (1000 words) 35%

Repeat Information

Repeat type: Internal

Costs

Costs associated with this module

Students are responsible for meeting the cost of essential textbooks, and of producing such essays, assignments, laboratory reports and dissertations as are required to fulfil the academic requirements for each programme of study.

In addition to this, students registered for this module typically also have to pay for:

Books and Stationery equipment

All journal articles used will be accessible to students through the University of Southampton electronic journals collection. There are no other cost implications arising from this module.

Please also ensure you read the section on additional costs in the University’s Fees, Charges and Expenses Regulations in the University Calendar available at www.calendar.soton.ac.uk.

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