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The University of Southampton

MEDI6241 Allergic Skin Disease

Module Overview

During this module, you will explore all aspects of allergic skin disease in depth. The module teaches about the immunological basis for skin diseases which can have an allergic component including eczema (atopic dermatitis), allergic contact dermatitis, photoallergic dermatitis, urticaria, angioedema, and systemic allergies affecting the skin. The sessions will include detail on pathogenesis, diagnosis, investigations and management. In addition, the module covers how to clinically distinguish allergic skin disease from other similar differential diagnoses. This module comprehensively covers both paediatric and adult disease.

Aims and Objectives

Learning Outcomes

Transferable and Generic Skills

Having successfully completed this module you will be able to:

  • Solve complex clinical and scientific issues systematically.
  • Formulate informed judgements in a clinical and/or scientific setting.
Disciplinary Specific Learning Outcomes

Having successfully completed this module you will be able to:

  • Discuss the different forms of hypersensitivity reactions (I to IV).
  • Evaluate the pathogenesis, diagnosis, investigation and management of skin allergy.
Cognitive Skills

Having successfully completed this module you will be able to:

  • Interpret diagnostic information from clinical scenarios of skin allergy.
  • Propose the differential diagnoses of inflammatory skin diseases such as eczema, and urticaria.


• Structure and function of skin • Type 1 allergy and the skin • Type II and III hypersensitivity mechanisms, overview, investigations and management • Clinical service delivery of allergic skin disease in children and adolescents, including transition services • How to recognise mast cell driven reactions in the skin e.g. urticaria • How to recognise cutaneous Type IV reactions e.g. allergic contact dermatitis, latex • Investigation and management of cutaneous reactions caused by systemic allergy • Allergic skin disease differential diagnosis • Chronic urticaria and angioedema • Urticarial variants e.g. physical • Atopic dermatitis • Other variants of eczema • Allergic contact dermatitis • Allergy to the sun

Learning and Teaching

Teaching and learning methods

A variety of learning and teaching methods will be adopted to promote a wide range of skills and meet the differing learning styles of the group. The techniques will include seminars, group work, practical demonstrations and exercises surrounding interpretation of data and clinical scenarios. Specialist lecturers from a range of academic and health care professional backgrounds will be used to ensure a breadth and depth of perspective is offered, giving a good balance between background theories and principles and practical management advice.

Independent Study82
Total study time100

Resources & Reading list

Rook's Textbook of Dermatology. Ardern-Jones MR, Flohr C, Reynolds NJ, et al. Atopic Eczema (Atopic Dermatitis). In: Griffiths CEM, Barker J, Bleiker T, et al. (eds.) Rook's Textbook of Dermatology. 9th ed. Oxford Wiley Blackwell; 2016. Note: library have the eBook of this new 9th edition.

American Academy of Dermatology Guidelines of care for the management of atopic dermatitis. Journal of the American Academy of Dermatology. 2014 Section 1-4.

Gawkrodger D and Ardern-Jones MR (2016). Dermatology: An Illustrated Colour Text. 

Useful Journals:.  Allergy Clinical Experimental Allergy Journal of Allergy and Clinical Immunology

Ardern-Jones MR, Hampton PJ, Vleugels RA (2017). Handbook of Dermatology Treatment. 

Global Atlas of Allergy. EAACI have produced an online Global Atlas of Allergy. To access the atlas, visit


Assessment Strategy

The assessment for the module provides you with the opportunity to demonstrate achievement of the learning outcomes. The Multiple Choice Question examination will be case-based, allowing you the opportunity to (1) demonstrate the depth and breadth of your knowledge of skin allergy, along with (2) showing higher cognitive skills and your ability to make sound judgements.


MethodPercentage contribution
Multiple choice question  (2 hours) 100%


MethodPercentage contribution
Multiple choice question  (2 hours) 100%

Repeat Information

Repeat type: Internal & External


Costs associated with this module

Students are responsible for meeting the cost of essential textbooks, and of producing such essays, assignments, laboratory reports and dissertations as are required to fulfil the academic requirements for each programme of study.

In addition to this, students registered for this module typically also have to pay for:


Computer: It is advisable that students provide their own laptop or personal computer, although shared facilities are available across the University campus.

Webcams and microphones: It is advisable that students provide their own webcam and microphone (integrated or USB/standalone) to take full advantage of the online support offered during the module.

Please also ensure you read the section on additional costs in the University’s Fees, Charges and Expenses Regulations in the University Calendar available at

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