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Research project: Improving continence in people with inflammatory bowel disease: active case-finding and a randomised controlled trial. (FINS)

Currently Active: 
Yes

To determine efficacy of postal v. face to face screening for reporting of faecal incontinence (FI) and uptake of interventions to improve continence in people with IBD. To determine effectiveness of IBD nurse specialist-led intervention v. self-help in reducing faecal incontinence (FI), other symptoms and costs, and improving quality of life. To determine patient & staff perspectives of experiences, acceptability and outcomes of interventions

Case-finding: the percentage of patients reporting FI will be estimated and predictors (age, gender, disease type and severity) will be investigated using logistic regression and presented as odds ratio and adjusted odds ratios. Randomisation will be stratified by centre and presence / absence of ileo-anal pouch, using random sized block of 2 to 6. St Mark’s faecal incontinence score at baseline and six months post-randomisation will be presented as means and SD by intervention arm. Effect of the intervention at six months will be estimated using a regression model adjusting for stratification factors, age and gender, and presented with 95% confidence intervals. All patients who provide data at six months will be included in the analysis, regardless of their compliance with the intervention (intention to treat).

 

Funder

This study is funded by NIHR (RfPB Competition 22: Ref number PB-PG-0613-31033) London North West Healthcare NHS Trust and the Chief Investigator is Professor Christine Norton in collaboration with King’s College London, St Mark’s Hospital Harrow, Guy’s and St Thomas’s NHS Trust, University College Hospital, Bart’s and the London, PCTU at Queen Mary University London, Crohn’s and Colitis UK

Related research groups

Health Work and Systems
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