Current research degree projects
Explore our current postgraduate research degree and PhD opportunities.
286 research degree projects
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Engineering
Developing cold plasma sterilisation system for lumened medical devises and complex space instruments
This project tackles the critical challenge of sterilising narrow channels in medical and space instruments. We will develop a novel hybrid cold plasma system, combining RF plasma with a DBD plasma, for deep channel penetration. Supported by industry expert Aurora, this research adapts space-derived technology to deliver a validated, safer sterilisation process for both space and medical domains. -
Chemistry and Chemical Engineering
Targeting the IRES structure of mRNA for modulating gene translation
This project targets mRNA IRES structures of oncogenes using modified oligonucleotides to avoid broad translational inhibition. We will optimise ON modifications, transfection, and efficacy in organoids, focusing on lung and blood cancers. The goal is an adaptable, highly selective technology for precise regulation of multiple oncoproteins.
Chemistry and Chemical EngineeringSynthesis of oligonucleotides and conjugates for targeted inhaled delivery to the lung
This project develops targeted delivery of antisense oligonucleotides for lung diseases such as cancer, asthma, and COPD. Conjugates will target lung cell receptors, with optimised linkers for recognition, transfection, and endosomal release. Designed for lung deposition, the system will be tested in organoid models, enabling novel, animal-free therapies.
Chemistry and Chemical EngineeringSynthesis of building blocks for evolution of polymerases
PCR has transformed DNA research but relies on specialised equipment. This project aims to develop a reversible linkage system forming dynamic oligonucleotide libraries to template DNA replication. The approach will be used to evolve novel ligases and polymerases, ultimately enabling medicinal applications, including targeted therapies for various cancers.
Chemistry and Chemical EngineeringEarly fault-tolerant quantum algorithms for drug discovery
This project aims to develop new early fault-tolerant quantum algorithms for drug discovery. You’ll design next-generation quantum algorithms, apply them to binding affinity, free-energy and spectroscopic predictions, and test them on real quantum hardware—advancing foundational theory, practical software development, and quantum use-cases.
Engineering | Mathematical sciencesControlling extreme events in fluid dynamics using modern optimization
Extreme bursts in fluid flows are hard to predict and control. This project develops modern optimisation and dynamical-systems tools to understand and limit these events using low-dimensional models. Biological sciencesUnderstanding immune cell interactions in the intestine
We are interested in how T cells are induced to become pathological in autoimmune conditions. In this project, the student will work with immunologists, clinicians and patients and will study the development of T cells in the context of Crohn’s disease.Physics and astronomyExcitons in hybrid semiconductor quantum dots for tunable emitters
Perovskite quantum dots show great potential for tunable light emitters. They are also promising candidates for single-photon emitters, which are key building blocks for quantum communication networks. This project will study the fundamental photophysics behind photon emission of perovskite semiconductor nanoparticles and develop new platforms for quantum technologies.Biological sciencesMechanisms of Cell Communication Driving Early Pancreatic Tumour Formation
This project investigates how secretory signalling pathways and cell communication influence the emergence of cancer stem cells (CSCs) during early pancreatic cancer development. Using advanced 3D organoid models, multi-omics, and genetic approaches, it aims to identify key pathways, biomarkers, and therapeutic targets for early detection and intervention in pancreatic ductal adenocarcinoma (PDAC).Chemistry and Chemical EngineeringInvestigation of fluorinated prolines by NMR spectroscopy
Some nasty peptides (conotoxins in carnivorous snails, neurotransmitter mimetics in snake venoms) contain uncommon conformers of the proline amino acid. This project is about controlling and measuring proline’s unusual dihedral angles, and improve nuclear magnetic resonance (NMR) methods to gather structural and dynamics information, using fluorinated prolines (FPro) as natural prolines' proxies.
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Find a PhD project
- A missing link between continental shelves and the deep sea: Have we underestimated the importance of land-detached canyons?
- A study of rolling contact fatigue in electric vehicles (EVs)
- Acoustic monitoring of forest exploitation to establish community perspectives of sustainable hunting
- Acoustic sensing and characterisation of soil organic matter
- Advancing intersectional geographies of diaspora-led development in times of multiple crises
- Aero engine fan wake turbulence – Simulation and wind tunnel experiments
- Against Climate Change (DACC): improving the estimates of forest fire smoke emissions
- All-in-one Mars in-situ resource utilisation (ISRU) system and life-supporting using non-thermal plasma
- An electromagnetic study of the continent-ocean transition southwest of the UK
- An investigation of the relationship between health, home and law in the context of poor and precarious housing, and complex and advanced illness
- Antibiotic resistance genes in chalk streams
- Being autistic in care: Understanding differences in care experiences including breakdowns in placements for autistic and non-autistic children
- Biogeochemical cycling in the critical coastal zone: Developing novel methods to make reliable measurements of geochemical fluxes in permeable sediments
- Bloom and bust: seasonal cycles of phytoplankton and carbon flux
- British Black Lives Matter: The emergence of a modern civil rights movement
- Building physics for low carbon comfort using artificial intelligence
- Business studies and management: accounting
- Business studies and management: banking and finance
- Business studies and management: decision analytics and risk
- Business studies and management: digital and data driven marketing
- Business studies and management: human resources (HR) management and organisational behaviour
- Business studies and management: strategy, innovation and entrepreneurship
- Carbon storage in reactive rock systems: determining the coupling of geo-chemo-mechanical processes in reactive transport
- Cascading hazards from the largest volcanic eruption in over a century: What happened when Hunga Tonga-Hunga Ha’apai erupted in January 2022?
- Characterisation of cast austenitic stainless steels using ultrasonic backscatter and artificial intelligence
- Climate Change effects on the developmental physiology of the small-spotted catshark
- Climate at the time of the Human settlement of the Eastern Pacific
- Collaborative privacy in data marketplaces
- Compatibility of climate and biodiversity targets under future land use change
- Cost of living in modern and fossil animals
- Creative clusters in rural, coastal and post-industrial towns
- Deep oceanic convection: the outsized role of small-scale processes
- Defect categories and their realisation in supersymmetric gauge theory
- Defining the Marine Fisheries-Energy-Environment Nexus: Learning from shocks to enhance natural resource resilience
- Design and fabrication of next generation optical fibres
- Developing a practical application of unmanned aerial vehicle technologies for conservation research and monitoring of endangered wildlife
- Development and evolution of animal biomineral skeletons
- Development of all-in-one in-situ resource utilisation system for crewed Mars exploration missions
- Ecological role of offshore artificial structures
- Effect of embankment and subgrade weathering on railway track performance
- Efficient ‘whole-life’ anchoring systems for offshore floating renewables
- Electrochemical sensing of the sea surface microlayer
- Engagement with nature among children from minority ethnic backgrounds
- Enhancing UAV manoeuvres and control using distributed sensor arrays
- Ensuring the Safety and Security of Autonomous Cyber-Physical Systems
- Environmental and genetic determinants of Brassica crop damage by the agricultural pest Diamondback moth
- Estimating marine mammal abundance and distribution from passive acoustic and biotelemetry data
- Evolution of symbiosis in a warmer world
- Examining evolutionary loss of calcification in coccolithophores
- Explainable AI (XAI) for health
- Explaining process, pattern and dynamics of marine predator hotspots in the Southern Ocean
- Exploring dynamics of natural capital in coastal barrier systems
- Exploring the mechanisms of microplastics incorporation and their influence on the functioning of coral holobionts
- Exploring the potential electrical activity of gut for healthcare and wellbeing
- Exploring the trans-local nature of cultural scene
- Facilitating forest restoration sustainability of tropical swidden agriculture
- Faulting, fluids and geohazards within subduction zone forearcs
- Faulting, magmatism and fluid flow during volcanic rifting in East Africa
- Fingerprinting environmental releases from nuclear facilities
- Flexible hybrid thermoelectric materials for wearable energy harvesting
- Floating hydrokinetic power converter
- Glacial sedimentology associated subglacial hydrology
- Green and sustainable Internet of Things
- How do antimicrobial peptides alter T cell cytokine production?
- How do calcifying marine organisms grow? Determining the role of non-classical precipitation processes in biogenic marine calcite formation
- How do neutrophils alter T cell metabolism?
- How well can we predict future changes in biodiversity using machine learning?
- Hydrant dynamics for acoustic leak detection in water pipes
- If ‘Black Lives Matter’, do ‘Asian Lives Matter’ too? Impact trajectories of organisation activism on wellbeing of ethnic minority communities
- Illuminating luciferin bioluminescence in dinoflagellates
- Imaging quantum materials with an XFEL
- Impact of neuromodulating drugs on gut microbiome homeostasis
- Impact of pharmaceuticals in the marine environment in a changing world
- Improving subsea navigation using environment observations for long term autonomy
- Information theoretic methods for sensor management
- Installation effect on the noise of small high speed fans
- Integrated earth observation mapping change land sea
- Interconnections of past greenhouse climates
- Investigating IgG cell depletion mechanisms
- Is ocean mixing upside down? How mixing processes drive upwelling in a deep-ocean basin
- Landing gear aerodynamics and aeroacoustics
- Lightweight gas storage: real-world strategies for the hydrogen economy
- Machine learning for multi-robot perception
- Machine learning for multi-robot perception
- Marine ecosystem responses to past climate change and its oceanographic impacts
- Mechanical effects in the surf zone - in situ electrochemical sensing
- Microfluidic cell isolation systems for sepsis
- Migrant entrepreneurship, gender and generation: context and family dynamics in small town Britain
- Miniaturisation in fishes: evolutionary and ecological perspectives
- Modelling high-power fibre laser and amplifier stability
- Modelling soil dewatering and recharge for cost-effective and climate resilient infrastructure
- Modelling the evolution of adaptive responses to climate change across spatial landscapes
- Nanomaterials sensors for biomedicine and/or the environment
- New high-resolution observations of ocean surface current and winds from innovative airborne and satellite measurements
- New perspectives on ocean photosynthesis
- Novel methods of detecting carbon cycling pathways in lakes and their impact on ecosystem change
- Novel technologies for cyber-physical security
- Novel transparent conducting films with unusual optoelectronic properties
- Novel wavelength fibre lasers for industrial applications
- Ocean circulation and the Southern Ocean carbon sink
- Ocean influence on recent climate extremes
- Ocean methane sensing using novel surface plasmon resonance technology
- Ocean physics and ecology: can robots disentangle the mix?
- Ocean-based Carbon Dioxide Removal: Assessing the utility of coastal enhanced weathering
- Offshore renewable energy (ORE) foundations on rock seabeds: advancing design through analogue testing and modelling
- Optical fibre sensing for acoustic leak detection in buried pipelines
- Optimal energy transfer in nonlinear systems
- Optimal energy transfer in nonlinear systems
- Optimizing machine learning for embedded systems
- Oxidation of fossil organic matter as a source of atmospheric CO2
- Partnership dissolution and re-formation in later life among individuals from minority ethnic communities in the UK
- Personalized multimodal human-robot interactions
- Preventing disease by enhancing the cleaning power of domestic water taps using sound
- Quantifying riparian vegetation dynamics and flow interactions for Nature Based Solutions using novel environmental sensing techniques
- Quantifying the response and sensitivity of tropical forest carbon sinks to various drivers
- Quantifying variability in phytoplankton electron requirements for carbon fixation
- Resilient and sustainable steel-framed building structures
- Resolving Antarctic meltwater events in Southern Ocean marine sediments and exploring their significance using climate models
- Robust acoustic leak detection in water pipes using contact sound guides
- Silicon synapses for artificial intelligence hardware
- Smart photon delivery via reconfigurable optical fibres
- The Gulf Stream control of the North Atlantic carbon sink
- The Mayflower Studentship: a prestigious fully funded PhD studentship in bioscience
- The calming effect of group living in social fishes
- The duration of ridge flank hydrothermal exchange and its role in global biogeochemical cycles
- The evolution of symmetry in echinoderms
- The impact of early life stress on neuronal enhancer function
- The oceanic fingerprints on changing monsoons over South and Southeast Asia
- The role of iron in nitrogen fixation and photosynthesis in changing polar oceans
- The role of singlet oxygen signaling in plant responses to heat and drought stress
- Time variability on turbulent mixing of heat around melting ice in the West Antarctic
- Triggers and Feedbacks of Climate Tipping Points
- Uncovering the drivers of non-alcoholic fatty liver disease progression using patient derived organoids
- Understanding recent land-use change in Snowdonia to plan a sustainable future for uplands: integrating palaeoecology and conservation practice
- Understanding the role of cell motility in resource acquisition by marine phytoplankton
- Understanding the structure and engagement of personal networks that support older people with complex care needs in marginalised communities and their ability to adapt to increasingly ‘digitalised’ health and social care
- Unpicking the Anthropocene in the Hawaiian Archipelago
- Unraveling oceanic multi-element cycles using single cell ionomics
- Unravelling southwest Indian Ocean biological productivity and physics: a machine learning approach
- Using acoustics to monitor how small cracks develop into bursts in pipelines
- Using machine learning to improve predictions of ocean carbon storage by marine life
- Vulnerability of low-lying coastal transportation networks to natural hazards
- X-ray imaging and property characterisation of porous materials
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- Black Futures Postgraduate Research Scholarships (Environmental and Life Sciences)
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