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Professor Stephen M Goldup PhD

Professor of Chemistry and Royal Society Wolfson Fellow

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Prof Steve Goldup joined Chemistry at the University of Southampton as Associate Professor of Supramolecular Chemistry and Royal Society Research Fellow in 2014. The Goldup Group investigate the synthesis and applications of rotaxanes as catalysts, sensors and materials.

We are fascinated by the way that linking molecules together using mechanical bonds can lead to new properties and applications

Steve obtained an MChem degree from the University of Oxford where he began his research career with a Part II project in the group of Sir Prof. Jack Baldwin. He continued his research training with a PhD in natural product synthesis under the supervision of Prof. Tony Barrett before shifting focus to apply his synthetic skills to the realisation of mechanically interlocked non-natural products during post doctoral work with Prof. David Leigh at the University of Edinburgh where in 2007 he was appointed as Fixed Term Lecturer in Organic Chemistry. In 2008 he moved to Queen Mary with the award of a Leverhulme Trust Early Career Fellowship and in October 2009 he was awarded a Royal Society University Research Fellowship. In October 2014 the group moved to the University of Southampton where Steve took up the position of Associate Professor. In August 2017, Steve was promoted to Professor of Chemistry and in 2019 he was awarded a Royal Society Wolfson Research Fellowship. Research in the Goldup Group focusses on the synthesis of novel mechanically interlocked molecules and their application as sensors, catalysts and materials.

Research interests

Our general research focus is on the synthesis and applications of mechanically interlocked molecules such as rotaxanes (an example of which is shown in the centre on the right) and catenanes. These challenging molecules have been shown to have potential applications in catalysis, drug delivery, electronic materials and sensing. We also investigate new synthetic methods and the underlying mechanism of organic reactions in order to develop molecular machines which carry out synthetic tasks to produce novel materials that are extremely hard to access in other ways - a trick we know can be used to great effect as many such devices are found in living cells!


PhD Supervision:

  • Andrew Heard
  • Jack Maynard
  • Theerapoom Boonprab
  • Shu Zhang
  • Matthew Fitzpatrick
  • Federica Rizzi
  • Arnau Rubio Rodriguez
  • Andrea Savoini


Research group

Functional Inorganic, Materials and Supramolecular Chemistry

Associate Editor of Chemical Science

Advisory Board member for Chemical Society Reviews

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Professor Stephen M Goldup
Chemistry, University of Southampton, Southampton SO17 1BJ, United Kingdom

Room Number: 30/4037

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