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The University of Southampton

HPRS1035 Scientific Basis of Cardiovascular/Respiratory and Sleep Science (part 2)

Module Overview

This module will consolidate and expand your knowledge and clinical practice. Clinical specialists will deliver the theoretical and practical aspects of this module. Using our dedicated clinical skills facility, you will apply the theory and perform a range of cardiac and respiratory tests on model patients before venturing out into your clinical placement.

Aims and Objectives

Module Aims

To ensure the student understands the breadth of the application of science across Cardiovascular/Respiratory & Sleep Science and is able to work safely within these environments.

Learning Outcomes

Learning Outcomes

Having successfully completed this module you will be able to:

  • Describe the role of Cardiology, Vascular, Respiratory & Sleep Science healthcare science practitioners in relevant patient pathways
  • Understand the application of safe and effective clinical practice in diagnostic physiological measurement including; 12 lead ECG Non-invasive blood pressure Spirometry Oxygen saturation
  • Understand the basic principles underpinning the routine investigations and procedures carried out in the diagnosis and treatment of cardiovascular and respiratory & sleep pathologies
  • Demonstrate an understanding of the importance of patient-centred care and effective MDT working in the investigation and treatment of patients.
  • Understand the pathophysiology underlying a range of common cardiovascular respiratory and sleep disorders.
  • Identify abnormal changes within physiological systems and measurements and relate to the underlying pathophysiology within cardiovascular respiratory and sleep science.


Application of safe and effective clinical practice in physiological measurement - Risk management - Infection control - Team working - Partners in the management of disease - Patient-centred care - Disability including learning disabilities - Children and adults - Communication skills Introduction to Cardiology and Vascular Science - Cardiac embryology and foetal developments - Cardiac and vascular pathophysiology Investigations and procedures carried out in the diagnosis and treatment of cardiac and vascular disease - Contextualise diagnostic data with respect to cardiac pathology - Characteristics of recording equipment and their evaluation - Ultrasound and physiological measurement systems in the evaluation of the vascular system - Common abbreviations and units Introduction to Respiratory and Sleep Science - Investigations and procedures carried out in the diagnosis and treatment of respiratory disease including sleep disorders - Characteristics of equipment and their evaluation - Calibration and quality control procedures - Pathophysiology of lung diseases - Communicable disease and microbiological hazards in the Respiratory Laboratory - Methods of sterilisation and disinfection - Physiological measurement systems in the evaluation of lung function - Dynamic lung volumes and transfer factors: mechanics and measurement - Physiological measurement systems used to measure respiration during sleep - Calculation of reference values - Pharmacology and therapeutics of bronchodilators

Special Features

This module embraces your contact with model patients in anticipation of your clinical placements. The combination and integration of our dedicated skills facility, the contribution from Patient Public Involvement (PPI) group and model patients provides you with the ultimate pre-placement experience.

Learning and Teaching

Teaching and learning methods

Students will learn by exploring material in seminars and laboratory practicals in conjunction with directed learning. Students will be encouraged to take responsibility for the development of their own learning by utilising a variety of means such as multimedia resources, and the library, and by self-directed development of the study skills necessary to access these resources

Independent Study312.5
Total study time374.5

Resources & Reading list

West, J. (2008). Pulmonary Pathophysiology The Essentials.. 

Aaronson, P. (2004). Cardiovascular System at a Glance. 

Lee-Chiong, T (2009). Sleep: a comprehensive handbook. 

Klabunde, R (2006). Cardiovascular Physiology Concepts. 

Morris, F (2008). The ABC of Clinical Electrocardiography. 

Marieb, E (2007). Human Anatomy & Physiology. 

Elsevier (2007). Fundamentals of sleep technology. 

Guyton, A (2009). Textbook of Medical Physiology. 

Cotes, J (2006). Lung function: physiology, measurement and application in medicine. 



Written exam


MethodPercentage contribution
Extended Matching Question (EMQ)  (1.5 hours) 50%
Written exam  (1.5 hours) 50%


MethodPercentage contribution
Assessment 100%

Repeat Information

Repeat type: External

Linked modules


To study this module, you will need to have studied the following module(s):

HPRS1034Scientific Basis of Cardiovascular/Respiratory and Sleep Science (part 1)


Costs associated with this module

Students are responsible for meeting the cost of essential textbooks, and of producing such essays, assignments, laboratory reports and dissertations as are required to fulfil the academic requirements for each programme of study.

In addition to this, students registered for this module typically also have to pay for:


There are no additional costs associated with this module.

Please also ensure you read the section on additional costs in the University’s Fees, Charges and Expenses Regulations in the University Calendar available at

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