Drug Allergy

Learning Outcomes

Learning Outcomes

Having successfully completed this module you will be able to:

• Interpret diagnostic information from clinical scenarios of drug allergy.
• Discuss the different forms of hypersensitivity reactions (I to IV).
• Evaluate approaches to improve patient-centred care through consideration of cultural circumstances and potential barriers to care.
• Propose the differential diagnoses of reaction patterns similar to drug allergic causes.
• Evaluate the pathogenesis, diagnosis, investigation and management of drug allergy.

The syllabus for the Drug Allergy module addresses the following themes and covers both adults and children:

• The immunological basis for drug allergy including type I to type IV hypersensitivity reactions.
• The presentations of different patterns of drug allergy.
• Differential diagnosis of drug allergy covering allergic reactions to ACE inhibitors, antibiotics, perioperative drugs, analgesics, vaccines and biologics.
• In vitro and in vivo investigations for drug allergy.
• Management of drug allergy reactions.
• Challenges and impact of drug allergy de-labelling

Teaching and learning methods

This online module is a blend of synchronous live and asynchronous recorded sessions and provides a flexible learning environment that gives you control over how, when and where you study. We strongly encourage you to plan your time so that you can attend our live teaching and make the most of being able to take part in rich discussions and interact with the teaching staff and your fellow students.

A variety of online learning and teaching methods will be adopted to promote the development of a wide range of skills. Specialist lecturers from a range of academic and health care professional backgrounds will be used to ensure a breadth and depth of perspective is offered, giving a good balance between background theories and principles and practical management advice.

In addition, by sharing their experience of living with allergy, patients will give an insight into their perspective, enabling you to develop your patient-centred approach. As well as the formal live teaching and recorded sessions, we offer group online tutorials to support student learning. There is also a guided immunology e-learning package with self-assessment available for students to explore in their own time. The self-assessment is formative and automated feedback is provided.

Resources & Reading list

General Resources

-Diagnosis and management of drug allergy in adults, children and young people: summary of NICE guidance. Dworzynski K, Ardern-Jones M et al. BMJ. 2014 Sep 3;349:g4852. doi: 10.1136/bmj.g4852.

3. Global Atlas of Allergy. EAACI have produced an online Global Atlas of Allergy. To access the atlas, visit http://www.eaaci.org/globalatlas/GlobalAtlasAllergy.pdf.

-Rook's Textbook of Dermatology. Griffiths CEM, Barker J, Bleiker T, et al. (eds.). Rook's Textbook of Dermatology 9th ed. Oxford: Wiley Blackwell; 2016. Chapters on adverse reactions to drugs (Ch 12) and benign cutaneous adverse reactions to drugs (Ch 18). Note: library have the eBook of this new 9th edition.

1. Talis reading list. Additional resources can be found on our Talis reading list which you can access from the module’s Blackboard site

4. Useful journals:. Allergy Clinical Experimental Allergy Journal of Allergy and Clinical Immunology

2. e-books. There are many e-Books available from the University of Southampton library in both allergy and related academic subjects. https://www-lib.soton.ac.uk/

-International Consensus on drug allergy.. Demoly et al. Allergy. 2014 Apr;69(4):420-37. International Consensus on drug allergy.

Textbooks

Holgate S, Church, M and Lichtenstein L (2011). Allergy. Philadelphia PA, USA: Elsevier.

Assessment strategy

The assessment for the module provides you with the opportunity to demonstrate achievement of the learning outcomes and to (1) demonstrate the depth and breadth of your knowledge of drug allergy, along with (2) showing higher cognitive skills and your ability to make sound judgements. The pass mark for the module and all assessed components is 50%.

Summative

This is how we’ll formally assess what you have learned in this module.

Referral

This is how we’ll assess you if you don’t meet the criteria to pass this module.

Repeat Information

Repeat type: Internal & External