Professor James Raftery MA, PhD

Professor of Health Technology Assessment, Chair NETSCC,Director Wessex Institute

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James is Professor of Health Technology Assessment at the University of Southampton and formerly chair of the NIHR Evaluation Trials and Studies Cooodinating Centre (NETSCC). He has led several research projects including most recently an update of the literature on assessing the impact of the HTA programme, and a report on “metadata" on the performance, conduct and results of clinical trials.

He is an active health economist, part of a group providing health economics input mainly to clinical trials. Research themes include the costs and benefits of clinical trials, overdiagnosis/overtreatment and the political economy of healthcare. He has written widely on health economic matters particularly relating to NICE, including a NICE blog on the BMJ website.

Qualifications

BA Economcis and Philsophy, 1972 Southamtpton University
MA Economics of Education and Science, UCD, 1974
PhD LSE 1993

Research

Responsibilities

Publications

Teaching

Contact

Research interests

Recent publications includes:

Treatment success in pragmatic randomized controlled trials: a review of trials funded by the UK Health Technology Assessment programme. L.Dent, J. Raftery. Trials 2011)
"Flogging dead horses": evaluating when have clinical trials achieved sufficiency and stability? A case study in cardiac rehabilitation. L Dent, J. Raftery .Trials 2011)
The CHD challenge: comparing four cost-effectiveness models. D. Turner, J Raftery, Jan;14(1):53-60. ... Turner D, Raftery J, Cooper K, Fairbank E, Palmer S, Ward S, Ara R. Accepted Value in Health. 2011.
Multiple Sclerosis risk sharing scheme: a costly failure. JR. BMJ, 340. 3/6/2010
Should NICE’s threshold range for cost per QALY be raised? No. James Raftery. BMJ 2009;338:b185, doi: 10.1136/bmj.b185 (Published 26 January 2009).
NICE and the challenge of cancer drugs. James Raftery BMJ 2009;338:b67, doi: 10.1136/bmj.b67 (Published 13 January 2009).
Payment to healthcare professionals for patient recruitment to trials: systematic review and qualitative study. J Raftery, J Bryant, J Powell, C Kerr, S Hawker. Health Technology Assessment 2008, Volume 12, no .10.)
The Birmingham rehabilitation uptake maximisation study (BRUM): a randomised controlled trial comparing home-based with centre-based cardiac rehabilitation. K Jolly, G Y H Lip, R S Taylor, J Raftery, J Mant, D Lane, S Greenfield, and A Stevens. Heart 2009; 95: 36-42. doi:10.1136/hrt.2007.127209. (Heart
See monograph report The Birmingham Rehabilitation Uptake Maximisation Study (BRUM). Home-based compared with hospital-based cardiac rehabilitation in a multi-ethnic population: cost-effectiveness and patient adherence. K Jolly,1* R Taylor,2 GYH Lip,3 S Greenfield,4 J Raftery,5 J Mant,4 D Lane,3 M Jones,4 KW Lee6 and A Stevens1 HTA Health Technology Assessment 2007; Vol 11: number 35.
Paying clinicians to join clinical trials: a review of guidelines and interview study of trialists James Raftery, Christine Kerr1, Sheila Hawker1 and John PowellTrials 2009, 10:15 doi:10.1186/1745-6215-10-15.
Payment to healthcare professionals for patient recruitment to trials: systematic review and qualitative study. J Raftery, J Bryant, J Powell, C Kerr, S Hawker. Health Technology Assessment 2008, Volume 12, no .10.
Aspirin in Alzheimer’s disease (AD200): a randomised open label trial. AD2000 Collaborative Group. Neurology Lancet. 7 January 2008. (see below for JR role in AD2000 Collaborative).
Paying for cost pharmaceuticals: regulation of new drugs in Australia, England and New Zealand. Raftery J. Medical Journal of Australia. 188, 1. 26-28. 7 January. 2008
An assessment of the impact of the NHS health technology assessment programme. S Hanney, M Buxton, C Green, D Coulson, J Raftery. Health Technology Assessment 2007. 11,53.
Assessing the impact of England's National Health Service R&D Health Technology Assessment program using the “payback” approach. James Raftery, Stephen Hanney, Colin Green and Martin Buxton, International Journal of Technology Assessment in Health Care (2009), 25: 1-5. DOI: 10.1017/S0266462309090011.
Ranibizumab (lucentis) versus bevacizumab (avastin): modelling cost effectiveness James Raftery, Jeremy Jones, Andew Clegg, and Andrew Lotery. British Journal of Ophthalmology. September 2007 91:1244-1246.
A brief pan management program compared with physical therapy for low back pain: results from an economic analysis alongside a randomized clinical trial. DG Whitehurst, M Lewis, GL Yao, S Bryan, JP Raftery, R Mullis EM Hay. Arthritis and Rheumatism. 57, 3, 2007. 466-473.
DNA may not mean ‘did not participate’: a qualitative study of reasons for non-adherence tat home and centre based cardiac rehabilitation Jones M, Jolly K, Raftery J, Lip GYH, Greeenfield S. on behalf of the BRUM Steering Group. Family Practice 2007 24: 343-357.
The Birmingham Rehabilitation Uptake Maximisation Study (BRUM). Home-based compared to hospital-based cardiac rehabilitation in a multi-ethnic population: cost effectiveness and patient adherence. Jolly K, Taylor R, Lip GYH, Greenfield S, Raftery J, Mant J, Land D, Jones M, Lee KW, Stevens A. Health Technology Assessment 2007, vol 13, No 35.
Screening versus routine practice in detection of atrial fibrillation in patients aged 65 or over: cluster randomised controlled trail. Fitzmaurice DA, Hobbs FDR, Jowett S, Mant J, Murray ET, Holder R, Raftery JP, Bryan S, Davies M, Lip GYH, Allan TF.BMJ, Aug 2007; 335: 383.
Warfarin versus aspirin for stroke prevention in an elderly community population with atrial fibrillation (the Birmingham atrial fibrillation treatment of the aged study, BAFTA): a randomised controlled trial. Mant J, Hobbs R, Fletcher K, Mant J, Fletcher K, et al; BAFTA investigators; Midland Research Practices Network (MidReC). Lancet 2007;370:493-503. (JR was member of BAFTA investigators.]
A systematic review and economic evaluation of epoetin alfa, epoetin beta and darbepoetin alfa in anaemia associated with cancer, especially that attributable to cancer treatment. J Wilson, GL Yao, J Raftery, J Bohlius, S Brunskill, J Sandercock, S Bayliss,P Moss, S Stanworth and C Hyde. Health Technology Assessment 2007 Volume 11, 13
Economic Evaluations of Calcineurin Inhibitors in Renal Transplantation: A Literature Review. Miners AH, Yao G, Raftery J, Taylor RS.Pharmacoeconomics. 2007;25:935-947.

Academic unit(s)

Primary Care & Population Sciences Academic Units

Research project(s)

BREATHE (Breathing Retraining for Asthma Trial of Home Exercise)

Although effective medicinal treatment exists for asthma, many people continue to have distressing symptoms and impaired quality of life. People with asthma have expressed interest in non-drug asthma treatments, particularly in breathing exercises. Several recent studies have shown benefits from a short course of breathing exercises taught by a respiratory physiotherapist for people with asthma who remained symptomatic despite usual treatment. We believe that many NHS patients could potentially benefit from these exercises, but unfortunately, there is currently not enough access to suitable trained physiotherapists able to provide such a service. We propose to provide the same breathing training programme that we have previously shown to be effective when taught 'face-to-face' by a physiotherapist in the form of a DVD, or internet download. Patients will use this in their own home at times convenient to them, in addition to their standard treatment (e.g. with inhalers). We will find out whether this type of instruction is better than the 'usual care' that is currently provided, and whether it is as good as the 'face to face' physiotherapist instruction (which is more expensive and less convenient for patients).

DIPSS

The DIPSS (Integrating Digital Interventions into Patient Self-Management Support) project has received funding of £2 million from the NIHR to examine patient digital self-management with healthcare professional support in primary care. Our aim is to develop digital behaviour change interventions for asthma and hypertension self-management, which will be examined in feasibility studies and full RCT (hypertension only). Issues surrounding the feasibility, acceptability, effectiveness and cost-effectiveness of digital intervention delivery will be explored with patients and healthcare professionals for each condition.

Currently supervising one PhD student

Provides health economics inputs on request to research bids from Southampton University. Currently providing health economics input to some 20 funded research projects.

NETSCC runs 5 UK wide research programmes for the National Insitute of Health Research (NIHR) . NETSCC also represents NIHR internationally.

Articles

Arden, N., Altman, D. G., Beard, D., Carr, A., Clarke, N., Collins, G., ... Raftery, J. (2017). Lower limb arthroplasty: can we produce a tool to predict outcome and failure, and is it cost-effective? An epidemiological study. NIHR Journals Library.

Little, P., Stuart, B., Hobbs, F. D. R., Kelly, J., Smith, E., Bradbury, K., ... Yardley, L. (2017). Randomised controlled trial and economic analysis of an internet-based weight management programme: POWeR+ (Positive Online Weight Reduction). Health Technology Assessment, 21(4). DOI: 10.3310/hta21040

Morgan, J. M., Kitt, S., Gill, J., McComb, J. M., Ng, G. A., Raftery, J., ... Cowie, M. (2017). Remote management of heart failure using implantable electronic devices. European Heart Journal. DOI: 10.1093/eurheartj/ehx227

Little, P., Stuart, B., Mullee, M., Thomas, T., Johnson, S., Leydon, G., ... Moore, M. (2016). A primary care randomised controlled trial of Steam inhalation and Nasal Irrigation For recurrent or chronic Sinus symptoms (SNIFS trial). Canadian Medical Association Journal, 1-24.

Little, P., Stuart, B., Hobbs, R. F. D., Kelly, J., Smith, E. R., Bradbury, K. J., ... Yardley, L. (2016). An internet-based intervention with brief nurse support to manage obesity in primary care (POWeR+): a pragmatic, parallel-group, randomised controlled trial. The Lancet Diabetes and Endocrinology, 4(10), 821-828.

Band, R., Morton, K., Stuart, B., Raftery, J., Bradbury, K., Yao, L., ... McManus, R. (2016). Home and Online Management and Evaluation of Blood Pressure (HOME BP) digital intervention for self-management of uncontrolled, essential hypertension: a protocol for the randomised controlled HOME BP trial. BMJ Open, 6(e012684), 1-13. DOI: 10.1136/bmjopen-2016-012684

Chakravarthy, U., Harding, S. P., Rogers, C. A., Downes, S., Lotery, A. J., Dakin, H. A., ... Reeves, B. C. (2015). A randomised controlled trial to assess the clinical effectiveness and cost-effectiveness of alternative treatments to Inhibit VEGF in Age-related choroidal Neovascularisation (IVAN). Health Technology Assessment, 19(78), 1-298. DOI: 10.3310/hta19780

Little, P., Stuart, B., Hobbs, F. D. R., Moore, M., Barnett, J., Popoola, D., ... Yardley, L. (2015). An internet-delivered handwashing intervention to modify influenza-like illness and respiratory infection transmission (PRIMIT): a primary care randomised trial. Lancet, 386(10004), 1631-1639. DOI: 10.1016/S0140-6736(15)60127-1

Williamson, I., Vennik, J., Harnden, A., Voysey, M., Perera, R., Kelly, S., ... Little, P. (2015). Effect of nasal balloon autoinflation in children with otitis media with effusion in primary care: an open randomized controlled trial. Canadian Medical Association Journal, 187(13), 961-969. DOI: 10.1503/cmaj.141608

Raftery, J., Young, A., & Buxton, H. (2015). Going beyond routine data collection of clinical trials funded by the health technology assessment programme. Trials, 16(S2). DOI: 10.1186/1745-6215-16-S2-P42

Bhurke, S., Cook, A., Tallant, A., Blatch-Jones, A., Williams, E., & Raftery, J. (2015). How are systematic reviews used in the planning and design of health technology assessment funded trials? Trials, 16(S2). DOI: 10.1186/1745-6215-16-S2-O3

Raftery, J., Young, A., & Blatch-Jones, A. (2015). Role of NIHR HTA clinical trials on subsequent systematic reviews. Trials, 16(S2). DOI: 10.1186/1745-6215-16-S2-P171

Bhurke, S., Cook, A., Tallant, A., Young, A., William, E., & Raftery, J. (2015). Using systematic reviews to inform NIHR HTA trial planning and design: a retrospective cohort. BMC Medical Research Methodology, 15(108), 1-7. DOI: 10.1186/s12874-015-0102-2

Dakin, H. A., Wordsworth, S., Rogers, C. A., Abangma, G., Raftery, J., Harding, S. P., ... Reeves, B. C. (2014). Cost-effectiveness of ranibizumab and bevacizumab for age-related macular degeneration: 2-year findings from the IVAN randomised trial. British Medical Journal, 4(7), 1-11. DOI: 10.1136/bmjopen-2014-005094

Raftery, J. P. (2014). NICE's cost-effectiveness range: should it be lowered? PharmacoEconomics, 32(7), 613-615. DOI: 10.1007/s40273-014-0158-6

Morgan, J. M., Dimitrov, B. D., Gill, J., Kitt, S., Ng, G. A., McComb, J. M., ... Cowie, M. R. (2014). Rationale and study design of the REM-HF study: remote management of heart failure using implanted devices and formalised follow-up procedures. European Journal of Heart Failure, 16(9), 1039-1045. DOI: 10.1002/ejhf.149

McCann, D. C., Thompson, M., Daley, D., Barton, J., Laver-Bradbury, C., Hutchings, J., ... Sonuga-Barke, E. (2014). Study protocol for a randomized controlled trial comparing the efficacy of a specialist and a generic parenting programme for the treatment of preschool ADHD. Trials, 15(1), 142. DOI: 10.1186/1745-6215-15-142

Culliford, D., Maskell, J., Judge, A., Arden, N. K., Cooper, C., Mullee, M., ... Barrett, D. (2013). A population-based survival analysis describing the association of body mass index on time to revision for total hip and knee replacements: results from the UK general practice research database. BMJ Open, 3(11), 1-9. DOI: 10.1136/bmjopen-2013-003614

Blatch-Jones, A., Raftery, J., Stanton, L., & Cook, A. (2013). Do NIHR health technology assessment randomised clinical trials perform as well as expected? Trials, 14(Suppl 1), P92. DOI: 10.1186/1745-6215-14-S1-P92

Raftery, J. (2013). How should we value future health? Was NICE right to change? Value in Health, 16(5), 699-700. DOI: 10.1016/j.jval.2013.03.001

Bruton, A., Kirby, S., Arden-Close, E., Taylor, L., Webley, F., George, S., ... Thomas, M. (2013). The BREATHE study: Breathing REtraining for Asthma - Trial of Home Exercises. A protocol summary of a randomised controlled trial. Primary Care Respiratory Journal, 22(2), PS1-PS7. DOI: 10.4104/pcrj.2013.00047

Raftery, J. (2013). Value based pricing: can it work? British Medical Journal, 347(f5941). DOI: 10.1136/bmj.f5941

Djulbegovic, B., Kumar, A., Glasziou, P. P., Perera, R., Reljic, T., Dent, L., ... Chalmers, I. (2012). New treatments compared to established treatments in randomized trials. Cochrane Database of Systematic Reviews, 10, 1-50. DOI: 10.1002/14651858.MR000024.pub3

Djulbegovic, B., Kumar, A., Glasziou, P. P., Perera, R., Reljic, T., Dent, L., ... Chalmers, I. (2012). New treatments compared to established treatments in randomized trials (Review). The Cochrane Library, (10). DOI: 10.1002/14651858

Raftery, J., Fairbank, E., Douet, L., Dent, L., Price, A., Milne, R., & Walley, T. (2012). Registration of noncommercial randomised clinical trials: the feasibility of using trial registries to monitor the number of trials. Trials, 13(1), 140. DOI: 10.1186/1745-6215-13-140

Dent, L., Taylor, R., Jolly, K., & Raftery, J. (2011). "Flogging dead horses": evaluating when have clinical trials achieved sufficiency and stability? A case study in cardiac rehabilitation. Trials, 12, 83. DOI: 10.1186/1745-6215-12-83

Lasseter, G. M., McNulty, C. A. M., Hobbs, F. D. R., Mant, D., Little, P., Barnett, J., ... for the PRImary care Streptococcal Management (PRISM) Investigators Group (2011). Effect of swab type on the analytical sensitivity of five point-of-care tests for group A streptococci. British Journal of Biomedical Science, 68(2), 91-94.

Raftery, J., & Chorozoglou, M. (2011). Possible net harms of breast cancer screening: updated modelling of Forrest report. British Medical Journal, 343, d7627. DOI: 10.1136/bmj.d7627

Young, A., Milne, R., Raftery, J., Dent, L., Turner, D., Davidson, P., & Cook, A. (2011). Research to meet the needs of the NHS: a review of published NIHR HTA clinical trials. Trials, 12, A86. DOI: 10.1186/1745-6215-12-S1-A86

Turner, D., Raftery, J., Cooper, K., Fairbank, E., Palmer, S., Ward, S., & Ara, R. (2011). The CHD challenge: comparing four cost-effectivess models. Value in Health, 14(1), 53-60. DOI: 10.1016/j.jval.2010.10.009

Dent, L., & Raftery, J. (2011). Treatment success in pragmatic randomised controlled trials: a review of trials funded by the UK Health Technology Assessment programme. Trials, 12, 109. DOI: 10.1186/1745-6215-12-109

Turner, D., Little, P., Raftery, J., Turner, S., Smith, H., Rumsby, K., ... on behalf of the UTIS team (2010). Cost effectiveness of management strategies for urinary tract infections: results from randomised controlled trial. BMJ, 340, c346. DOI: 10.1136/bmj.c346

Cutress, R. I., McDowell, A., Gabriel, F. G., Gill, J., Jeffrey, M. J., Agrawal, A., ... Yiangou, C. (2010). Observational and cost analysis of the implementation of breast cancer sentinel node intra-operative molecular diagnosis. Journal of Clinical Pathology, 63(6), 522-9. DOI: 10.1136/jcp.2009.072942

Culliford, D., Maskell, J., Beard, D., Murray, D., Price, A., Arden, N. K., ... Raftery, J. (2010). Temporal trends in hip and knee replacement in the United Kingdom: 1991-2006. The Journal of Bone and Joint Surgery, 92B(1), 130-135. DOI: 10.1302/0301-620X.92B1.22654

Yardley, L., Kirby, S., Barker, F., Little, P., Raftery, J., King, D., ... Mullee, M. (2009). An evaluation of the cost-effectiveness of booklet-based self-management of dizziness in primary care, with and without expert telephone support. BMC Ear, Nose and Throat Disorders, 9(13), 1-12. DOI: 10.1186/1472-6815-9-13

Raftery, J., Hanney, S., Green, C., & Buxton, M. (2009). Assessing the impact of England's National Health Service R&D Health Technology Assessment program using the “payback” approach. International Journal of Technology Assessment in Health Care, 25(1), 1-5. DOI: 10.1017/S0266462309090011

Jones, R., Sheehan, B., Phillips, P., Juszczak, E., Adams, J., Baldwin, A., ... Howard, R. (2009). DOMINO-AD protocol: donepezil and memantine in moderate to severe Alzheimer's disease - a multicentre RCT. Trials, 10, 57. DOI: 10.1186/1745-6215-10-57

Lasseter, G., McNulty, C., Hobbs, F., Mant, D., Little, P., Barnett, J., ... PRISM Investigators (2009). In vitro evaluation of five rapid antigen detection tests for group A beta-haemolytic streptococcal sore throat infections. Family Practice, 26(6), 437-444. DOI: 10.1093/fampra/cmp054

Raftery, J. (2009). NICE and the challenge of cancer drugs. BMJ, 338. DOI: 10.1136/bmj.b67

Raftery, J., & Dent, L. (2009). Should avastin be used to treat age-related macular degeneration in the NHS? – Yes. Eye, 23(6), 1247-1249. DOI: 10.1038/eye.2009.85

Jolly, K., Lip, G. Y. H., Taylor, R. S., Raftery, J., Mant, J., Lane, D., ... Stevens, A. (2009). The Birmingham rehabilitation uptake maximisation study (BRUM): a randomised controlled trial comparing home-based with centre-based cardiac rehabilitation. Heart, 95(1), 36-42. DOI: 10.1136/hrt.2007.127209

Raftery, J., Bentham, P., Gray, R., Hills, R., Crome, P., Sellwood, E., & AD2000 Collaborative Group (2008). Aspirin in Alzheimer's disease (AD2000): a randomised open label trial. Lancet Neurology, 7(1), 41-49. DOI: 10.1016/S1474-4422(07)70293-4

Raftery, J. P. (2008). Paying for costly pharmaceuticals: regulation of new drugs in Australia, England and New Zealand. Medical Journal of Australia, 188(1), 26-28.

Raftery, J., Bryant, J., Powell, J., Kerr, C., Hawker, S., & NCCHTA (2008). Payment to healthcare professionals for patient recruitment to trials: systematic review and qualitative study. Health Technology Assessment, 12(10), 1-128.

Cooper, K., Davies, R., Raftery, J., & Roderick, P. (2008). Use of a coronary heart disease simulation model to evaluate the costs and effectiveness of drugs for the prevention of heart disease. Journal of the Operational Research Society, 59(9), 1173-1181. DOI: 10.1057/palgrave.jors.2602468

Whitehurst, D. G. T., Lewis, M., Yao, G. L., Bryan, S., Raftery, J. P., Mullis, R., & Hay, E. M. (2007). A brief pain management program compared with physical therapy for low back pain: results from an economic analysis alongside a randomized clinical trial. Arthritis & Rheumatism, 57(3), 466-473. DOI: 10.1002/art.22606

Miners, A. H., Yao, G., Raftery, J., & Taylor, R. S. (2007). Economic evaluations of calcineurin inhibitors in renal transplantation: a literature review. PharmacoEconomics, 25(11), 935-947.

Raftery, J. P., & Lotery, A. (2007). Letter. The cheaper drug, bevacizumab, should be referred to NICE. BMJ, 334(381), 381-382. DOI: 10.1136/bmj.39128.708565.3A

Raftery, J., Clegg, A., Jones, J., Tan, S. C., & Lotery, A. (2007). Ranibizumab (Lucentis) versus bevacizumab (Avastin): modelling cost effectiveness. British Journal of Ophthalmology, 91(9), 1244-1246. DOI: 10.1136/bjo.2007.116616

Fitzmaurice, D. A., Hobbs, F. D., Jowett, S., Mant, J., Murray, E. T., Holder, R., ... Allan, T. F. (2007). Screening versus routine practice in detection of atrial fibrillation in patients aged 65 or over: cluster randomised controlled trial. BMJ, 335(7616), 1-6. DOI: 10.1136/bmj.39280.660567.55

McCabe, C., Tsuchiya, A., Claxton, K., & Raftery, J. (2006). Orphan drugs revisited. QJM: An International Journal of Medicine, 99(5), 341-345. DOI: 10.1093/qjmed/hcl033

Raftery, J. (2006). Review of NICE's recommendations, 1999-2005. BMJ, 332(7552), 1266-1268. DOI: 10.1136/bmj.332.7552.1266

Chase, D., Roderick, P., Cooper, K., Davies, R., Quinn, T., & Raftery, J. (2006). Using simulation to estimate the cost effectiveness of improving ambulance and thrombolysis response times after myocardial infarction. Emergency Medicine Journal, 23(1), 67-72. DOI: 10.1136/emj.2004.023036

Hobbs, F. D. R., Fitzmaurice, D. A., Mant, J., Murray, E., Jowett, S., Bryan, S., ... Lip, G. (2005). A randomised controlled trial and cost-effectiveness study of systematic screening (targeted and total population screening) versus routine practice for the detection of atrial fibrillation in people aged 65 and over. The SAFE study. Health Technology Assessment, 9(40), [93pp].

Stevens, A. J., Raftery, J., & Roderick, P. (2005). Can health technologies be assessed using routine data? International Journal of Technology Assessment in Health Care, 21(1), 96-103. DOI: 10.1017/S0266462305050129

Woodroffe, R., Yao, G. L., Meads, C., Bayliss, S., Ready, A., Raftery, J., & Taylor, R. S. (2005). Clinical and cost-effectiveness of newer immunosuppressive regimens in renal transplantation: a systematic review and modelling study. Health Technology Assessment, 9(21), 1. DOI: 10.3310/hta9210

Mohammed, M. A., Mant, J., Bentham, L., & Raftery, J. (2005). Comparing processes of stroke care in high- and low-mortality hospitals in the West Midlands, UK. International Journal for Quality in Health Care, 17(1), 31-36. DOI: 10.1093/intqhc/mzh088

Raftery, J. P., Yao, G. L., Murchie, P., Campbell, N. C., & Ritchie, L. D. (2005). Cost effectiveness of nurse led secondary prevention clinics for coronary heart disease in primary care: follow up of a randomised controlled trial. BMJ, 330(7493), 707-710. DOI: 10.1136/bmj.38342.665417.8F

Wilson, J., Connock, M., Song, F., Yao, G., Fry-Smith, A., Raftery, J., & Peake, D. (2005). Imatinib for the treatment of patients with unresectable and/or metastatic gastrointestinal stromal tumours: systematic review and economic evaluation. Health Technology Assessment, 9(25), 1. DOI: 10.3310/hta9250

Fitzmaurice, D. A., Murray, E. T., McCahon, D., Holder, R., Raftery, J. P., Hussain, S., ... Hobbs, F. D. R. (2005). Self management of oral anticoagulation: randomised trial. BMJ, 331(7524), 1057-1059. DOI: 10.1136/bmj.38618.580903.AE

Mohammed, M., Raftery, J., LeatherBarrow, M., Harley, M., & Marshall, T. (2004). Counting in-hospital deaths in England: a comparison of hospital computer systems and mortuary registers. Journal of Health Services Research and Policy, 9(2), 100-103. DOI: 10.1258/135581904322987517

Courtney, C., Farrell, D., Gray, R., Hills, R., Lynch, L., Sellwood, E., ... AD2000 Collaborative Group (2004). Long-term donepezil treatment in 565 patients with Alzheimer's disease (AD2000): randomised double-blind trial. Lancet, 363(9427), 2105-2115. DOI: 10.1016/S0140-6736(04)16499-4

McCahon, D., Fitzmaurice, D. A., Murray, E. T., Fuller, C. J., Hobbs, R. F. D., Allan, T. F., & Raftery, J. P. (2003). SMART: self-management of anticoagulation, a randomised trial [ISRCTN19313375]. BMC Family Practice, 4(11), [7pp]. DOI: 10.1186/1471-2296-4-11

Song, F., Raftery, J., Aveyard, P., Hyde, C., Barton, P., & Woolacott, N. (2002). Cost-effectiveness of pharmacological interventions for smoking cessation: a literature review and a decision analytic analysis. Medical Decision Making, 22(5 Suppl), S26-S37. DOI: 10.1177/027298902237708

Woolacott, N. F., Jones, L., Forbes, C. A., Mather, L. C., Sowden, A. J., Song, F. J., ... Barton, P. M. (2002). The clinical effectiveness and cost-effectiveness of bupropion and nicotine replacement therapy for smoking cessation: a systematic review and economic evaluation. Health Technology Assessment, 6(16), [245pp].

Kendrick, T., Stevens, L., Bryant, A., Goddard, J., Stevens, A., Raftery, J., & Thompson, C. (2001). Hampshire Depression Project: changes in the process of care and cost consequences. British Journal of General Practice, 51(472), 911-913.

Raftery, J. (2001). NICE: faster access to modern treatments? Analysis of guidance on health technologies. BMJ, 323(7324), 1300-1303. DOI: 10.1136/bmj.323.7324.1300

Reports

Raftery, J., Hanney, S., Greenhalgh, T., Glover, M., & Blatch-Jones, A. J. (2016). Models and applications for measuring the impact of health research: update of a systematic review for the Health Technology Assessment programme. (Health Technology Assessment; Vol. 20, No. 76). Southampton, GB: NIHR Journals Library. DOI: 10.3310/hta20760

Chakravarthy, U., Harding, S. P., Rogers, C. A., Downes, S., Lotery, A. J., Dakin, H. A., ... Reeves, B. C. (2015). A randomised controlled trial to assess the clinical effectiveness and cost-effectiveness of alternative treatments to Inhibit VEGF in Age-related choroidal Neovascularisation (IVAN). (Health Technology Assessment; No. 19(78)). Southampton, GB: NIHR Journals Library. DOI: 10:33:10/hta19780

Raftery, J., Young, A., Stanton, L., Milne, R., Cook, A., Turner, D., & Davidson, P. (2015). Clinical trial metadata: defining and extracting metadata on the design, conduct, results and costs of 125 randomised clinical trials funded by the National Institute for Health Research Health Technology Assessment programme. (Health Technology Assessment; No. 19). Southampton, GB: NIHR Journals Library. DOI: 10.3310/hta19110

Little, P., Hobbs, F. D. R., Moore, M., Mant, D., Williamson, I., McNulty, C., ... Mullee, M. (2014). PRImary care Streptococcal Management (PRISM) study: in vitro study, diagnostic cohorts and a pragmatic adaptive randomised controlled trial with nested qualitative study and cost-effectiveness study. (HTA Journal Series; Vol. 18, No. 6). Southampton, GB: NIHR Journals Library. DOI: 10.3310/hta18060

Wilson, J., Yao, G. . L., Raftery, J., Bohlius, J., Brunskill, S., Sandercock, J., ... Hyde, C. (2007). A systematic review and economic evaluation of epoetin alpha,epoetin beta and darbepoetin alpha in anaemia associated with cancer, especially that attributable to cancer treatment. Health Technology Assessment. DOI: 10.3310/hta11130

Health economics
Overtreatment
Clinical trials
NICE
Use of routine data in HTA

Professor James Raftery
Faculty of Medicine, University of Southampton, Building 85, Life Sciences Building, Highfield Campus, Southampton, SO171BJ

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