About
Ivo Tews uses crystallography to study molecular interactions. Particular intrests are in large dynamic macromolecular complexes and time resolved techniques. As a member of the CCP4 project for crystallographic software he chairs working group 2, and is engaged in Synchrotron Science at the Diamond Light Source and the EUropean Synchtrotron Radiation Facilty.
Research
Research groups
Research interests
- Natural products biosynthesis: a complex cascade of catalytic steps in vitamin B6 biosynthesis is characterised by structures or reaction intermediates in the large PLP syntase complexEdit
- Bacterial biofilms: understanding of RedOx regulated phosphodiesterase activity in dispersal of biofilms to address chronic infections
- Cancer immunology: together with Cancer Immunology at Southampton we use a structure based apporach in developing novel cancer therapie
Research projects
Active projects
Researchers:
Researchers:
Sponsor: Science And Technology Facilities Council
Sponsor: Medical Research Council
Researchers:
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Sponsor: Cancer Research UK
Researchers:
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Sponsor: EPSRC
Completed projects
Researchers:
Researchers:
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Researchers:
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Sponsor: Cancer Research UK
Researchers:
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Sponsor: Wessex Medical Research
Publications
61 publications
Page 2 of 7
Muchaala Yeboah,
Charys Papagregoriou,
Des C. Jones,
Guangan Hu,
Justine McPartlan,
Christopher Mockridge,
Ivo Tews,
Martin Glennie,
, 2020
, JCI Insight
, 5 (18)
Type: article
Dom Bellini,
Andrew Hutchin,
Odel Soren,
Ivo Tews,
& Martin A. Walsh
, 2020
Type: bookChapter
Xiaojie Yu,
Hayden Fisher,
Christine A. Penfold,
Jinny Kim,
Tatyana Inzhelevskaya,
C. Ian Mockridge,
Ruth R. French,
Leon R. Douglas,
Vikki English,
J. Sjef Verbeek,
Ann L. White,
Ivo Tews,
Martin J. Glennie,
, 2020
, Cancer Cell
, 37 (6) , 850--866.e7
Type: article
Selina L S Storm,
Adam D Crawshaw,
Nicholas E Devenish,
Rachel Bolton,
David R Hall,
Ivo Tews,
& Gwyndaf Evans
, 2020
, IUCrJ
, 7 (Part 1) , 129--135
Type: article
Yu-Ming Cai,
Andrew Hutchin,
Jack Craddock,
Martin A Walsh,
& Ivo Tews
, 2020
, Scientific Reports
, 10 (1) , 1--12
Type: article
Marina Lučić,
Dimitri A. Svistunenko ,
Michael T. Wilson,
Amanda K. Chaplin,
Bradley Davy,
Ali Ebrahim,
Danny Axford,
Takehiko Tosha,
Hiroshi Sugimoto,
Shigeki Owada,
Florian S. N Dworkowski,
Ivo Tews,
Robin L. Owen,
Michael A. Hough,
& Jonathan A. R. Worrall
, 2020
, Angewandte Chemie International Edition
, 59 (48) , 21656–21662
Type: article
Maria Victoria Humbert,
Alexandra Jackson,
Christian M. Orr,
& Myron Christodoulides
, 2019
, Scientific Reports
, 9 (1) , 1--14
Type: article
Greta Reintjes,
Halina E. Tegetmeyer,
Miriam Bürgisser,
Sandi Orlić,
Ivo Tews,
Mikhail Zubkov,
Daniela Voß,
Oliver Zielinski,
Christian Quast,
Frank Oliver Glöckner,
Rudolf Amann,
Timothy G. Ferdelman,
& Bernhard M. Fuchs
, 2019
, Applied and Environmental Microbiology
, 85 (14) , 1--14
DOI: 10.1128/AEM.00184-19
Type: article
John H. Beale,
Rachel Bolton,
Stephen A. Marshall,
Emma V. Beale,
Stephen B. Carr,
Ali Ebrahim,
Tadeo Moreno-Chicano,
Michael A. Hough,
Jonathan A.R. Worrall,
Ivo Tews,
& Robin L. Owen
, 2019
, Journal of Applied Crystallography
, 52 (Pt 6) , 1385--1396
Type: article
Hannia, Liliana Almonacid Mendoza,
Maria Humbert,
Aiste Dijokaite,
David Cleary,
Yiwen Soo,
Miao-chiu Hung,
Christian M. Orr,
Ivo Tews,
& Moritz M. Machelett
, 2018
, mSphere
, 10 (3) , 1--25
Type: article
Pagination
Biography
Prizes
- David Blow Prize (2011)
- PD, venia legendi (2011)