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Research project

Developing immunostimulatory antibodies to deliver agonism without toxicity

Staff

Lead researcher

Professor Aymen Al-Shamkhani

Professor in Immunology

Research interests

  • Cancer Immunotherapy
  • Immunobiology of costimulatory receptors
  • Immunostimulatory antibodies
Connect with Aymen
Other researchers

Professor Jonathan Essex

Professor
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Professor Mark Cragg

Professor in Experimental Cancer Biology

Research interests

  • Antibody biology
  • Antibody engineering
  • Cancer Immunotherapy
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Professor Stephen Beers

Professor of Immunology & Immunotherapy
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Professor Peter Johnson CBE MD FRCP FMedSci

Professor of Medical Oncology
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Dr Ali Roghanian PhD, FHEA

Associate Professor

Research interests

  • Cancer immunotherapy
  • Monoclonal antibodies
  • Immunoinhibitory receptors
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Dr Ivo Tews

Associate Professor

Research interests

  • Natural products biosynthesis: a complex cascade of catalytic steps in vitamin B6 biosynthesis is characterised by structures or reaction intermediates in the large PLP syntase complexEdit
  • Bacterial biofilms: understanding of RedOx regulated phosphodiesterase activity in dispersal of biofilms to address chronic infections
  • Cancer immunology: together with Cancer Immunology at Southampton we use a structure based apporach in developing novel cancer therapie
Connect with Ivo

Collaborating research institutes, centres and groups

Research outputs