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Miss Abi Sudol

 PhD
Research Fellow

Research interests

  • Structural biology
  • Antibody-degrading enzymes
  • Antibody glycoengineering

More research

Connect with Abi

Email: a.sudol@soton.ac.uk

ORCID

Profile photo 
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Name 
To change your name or prefix title contact Ask HR (opens in new tab)  If you want to update an academic title you'll need to provide evidence e.g. a PhD certificate. The way your name is displayed is automatic and cannot be changed. You can also update your post-nominal letters in Subscribe (opens in a new tab).

Job title 
Raise a request through ServiceNow (opens in a new tab) to change your job title (40 characters maximum) unless you're on the ERE career pathway. If you're on the ERE path you can not change your main job title, but you can request other minor updates through Ask HR (opens in new tab). If you have more than one post only your main job title will display here, but you can add further posts or roles in other sections of your profile.

Research interests (for researchers only) 
Add up to 5 research interests. The first 3 will appear in your staff profile next to your name. The full list will appear on your research page. Keep these brief and focus on the keywords people may use when searching for your work. Use a different line for each one.

In Pure (opens in a new tab), select ‘Edit profile’. Under the heading 'Curriculum and research description', select 'Add profile information'. In the dropdown menu, select 'Research interests: use separate lines'.

Contact details 
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You can link to your Google Scholar, LinkedIn and Twitter accounts through Pure (opens in a new tab). Select ‘Edit profile’.  In the 'Links' section, use the 'Add link' button. 

ORCID ID 
Create or connect your ORCID ID in Pure (opens in a new tab). Select ‘Edit profile’ and then 'Create or Connect your ORCID ID'.

Accepting PhD applicants (for researchers only) 
Choose to show whether you’re currently accepting PhD applicants or not in Pure (opens in a new tab). Select ‘Edit profile’. In the 'Portal details' section, select 'Yes' or 'No' to indicate your choice. 

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About

A common immune evasion mechanism utilised by pathogens is the inactivation of the host immune system. The prevalent human pathogen Streptococcus pyogenes exemplifies this, by secretion of multiple enzymes which specifically modify and inactivate human IgG antibodies, which are vital in adaptive immunity. The exquisite specificity of these enzymes for human IgG has driven their clinical use in dampening unwanted immune responses, such as during organ transplantation, autoimmune disease and cancer immunotherapy. During her PhD studies, Abigail investgated the structural basis of several antibody-degrading enzymes from S.pyogenes (named IdeS, EndoS and EndoS2) binding to their human IgG Fc target, generating crystal structures of these enzyme-antibody complexes. These studies will now be utilised in further research to develop novel antibody-modulating enzymes, using a combination of structural rationale and computational protein design.

You can update this in Pure (opens in a new tab). Select ‘Edit profile’. Under the heading and then ‘Curriculum and research description’, select ‘Add profile information’. In the dropdown menu, select - ‘About’.

Write about yourself in the third person. Aim for 100 to 150 words covering the main points about who you are and what you currently do. Clear, simple language is best. You can include specialist or technical terms.

You’ll be able to add details about your research, publications, career and academic history to other sections of your staff profile.

Update this section in Pure