Research project

Droplet microfluidic based chemical sensors for rapid measurement of nutrients in water

Project overview

Traditionally most chemical parameters (e.g. nitrate, phosphate) in aquatic environment are measured by laboratory analysis of discrete water samples. Microfluidic sensors offer an attractive alternative: by taking and analysing samples autonomously in situ, they obviate sampling allowing larger datasets particularly when used in conjunction with autonomous systems. The current state-of-the-art sensors have temporal resolution of minutes due to Taylor dispersion (fluid flow effectively smears chemical composition within the device) and complex valve controls, making them high-cost and unsuitable for deployments requiring high frequency measurement - most notably on profiling vehicles (e.g. Argo floats, oceanic gliders) that rapidly transect the water column. Droplet microfluidics (in which nano litre water samples are taken and subsequently operated on as droplets within an immiscible oil) is a novel microfluidic method that, in addition to other advantages, crucially offers zero Taylor dispersion and much higher analytical throughput. This project will develop the first-ever droplet-flow based field-deployable sensor for autonomous systems. Low-cost, low-powered and fully functional; the device will be a step-change in high-frequency autonomous aquatic chemical analysis.

Staff

Lead researchers

Professor Xize Niu

Professor of Biosensing&Microengineering
Research interests
  • Microfluidics
  • Lab-on-a-chip
  • Sensors
Connect with Xize

Other researchers

Dr Adrian Nightingale

Associate Professor
Research interests
  • Microfluidics.
  • Sensors.
  • Analytical chemistry.
Connect with Adrian

Professor Hywel Morgan MBE

Professor of Bioelectronics
Research interests
  • Microfluidics
  • Bio-sensors
  • Lab-on-a-chip technologies
Connect with Hywel

Collaborating research institutes, centres and groups

Research outputs

Bingyuan Lu, James Lunn, Ken Yeung, Selva Dhandapani, Liam Carter, Tiina Roose, Liz Shaw, Adrian Nightingale & Xize Niu, 2024, Environmental Science & Technology, 58(6), 2956-2965
Type: article
Chi Leng Leong, Sharon Coleman, Adrian Nightingale, Sammer-Ul Hassan, David Voegeli, Martyn G. Boutelle & Xize Niu, 2019, Analytical Methods, 11(48), 6119-6123
Type: article
Adrian Nightingale, Sammer-Ul Hassan, Brett Warren, Kyriacos Makris, Gareth W.H. Evans, Evanthia Papadopoulou, Sharon Coleman & Xize Niu, 2019, Environmental Science & Technology, 53(16), 9677-9685
Type: article
Adrian Nightingale, Sammer-Ul Hassan, Gareth, William Harry Evans, Sharon Coleman & Xize Niu, 2018, Lab on a Chip
Type: article
Adrian Nightingale, Gareth Evans, Peixiang Xu, Byung Jae Kim, Sammer-Ul Hassan & Xize Niu, 2017, Lab on a Chip, 17(6), 1149-1157
Type: article