Research project

Investigating the role of tauopathy-induced activating transcription factor 3: a transcriptional hub to modulate neurodegeneration

Research groups:

Neuroscience
Lead researcher:

Professor Katrin Deinhardt
Status:

Active

Project overview

Alzheimer's Society

Staff

Lead researcher

Professor Katrin Deinhardt

Professor

Research interests

Our research is focused on cellular and molecular neurobiology. Fascinated by the beautiful but complicated shape of individual neurons, we study the complex intracellular logistics required to form, maintain and remodel these cells throughout life.Neurons extend processes that cover vast territories, which allow them to directly connect with cells distant from the soma. Our research interest is to understand how neurons integrate the different extracellular cues that they receive at distinct parts of the cell in time and space to maintain and adapt their structure and connectivity. To this end, we investigate the interplay of short- and long-range trafficking and signalling, and how these events ultimately converge to initiate changes in neuronal morphology and physiology in health and neurodegeneration.
Lab webpage

Email: k.deinhardt@soton.ac.uk

Collaborating research institutes, centres and groups

Neuroscience

We work on national and global priorities of health and well-being, underpinning research in neuroscience, and age-related neurodegenerative diseases, including Alzheimer’s.