The criticality of Cu, Co (+/- V) in battery technology and electricity transmission has established them as key components of the carbon-free energy transition. A major proportion of these elements are sourced from sedimentary basin-hosted deposits, formed from large-scale fluid flow systems. Recent work has shown that diverse basin architectures and processes were responsible for their genesis, yet we still do not understand why so few basins become highly endowed with metals. Given their paucity, the geological evolution of such basins demands the juxtaposition of unique conditions that: (1) generated large volumes of metal-bearing fluid; (2) provided sufficient sulfur; (3) created reducing trap sites; and (4) focused fluid flow into these sites . Understanding large deposits is particularly significant because they are efficient to mine and offer the greatest societal benefits. Our particular focus is to develop and integrate mineral and petroleum systems approaches to provide a disruptive innovation opportunity in the science and industrial applications in this field. Our objectives are to identify the processes, operating over a range of scales, that lead to the formation of large Cu-Co-(V) deposits and derive new and practical exploration tools. The opportunity is timely, given the current wave of academic interest in these ore systems, and the increased collaboration between industry and academia to develop sophisticated methods that can reduce exploration costs, risk and environmental impact. To tackle these challenges, we have assembled a multi-institute academic consortium with internationally-recognised expertise across the geosciences. We have also built strategic research alliances with: (1) the UK's major mining houses, Rio Tinto and Anglo American, and with BHP and First Quantum Minerals, all with global interests in sediment-hosted copper mineralisation; (2) the energy sector (Scheupbach Energy); and (3) international academic partners (CSIRO, Univ. Houston, GFZ Potsdam, Universidad Nacional, Buenos Aires. The collaboration between PIs, PDRAs, affiliated PhD students funded outside the grant, industry and international partners will deliver high impact scientific publications, new data and tools to support the development of lower risk mineral exploration strategies, and highlight the UK as a world-leading community for research in basin-hosted mineral systems.