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Research project

Simpson - Diversity in blood flow control to the brain: moving from individualised modelling towards personalised treatment of the injured brain

Staff

Lead researchers

Professor David Simpson

Prof of Biomedical Signal Processing
Research interests
  • Biomedical signal processing with applications in neurophysiology and cardio-vascular and cerebro-vascular control
  • Blood flow control in the brain (how does the brain regulate is own blood supply and how to detect impairment of this function)
  • Auditory evoked potentials (methods to detect the small electrical responses of the brain to auditory stimulation for the assessment of various hearing disorders)
Connect with David

Email: ds@isvr.soton.ac.uk

Collaborating research institutes, centres and groups

Research outputs

Estimating confidence intervals for cerebral autoregulation: a parametric bootstrap approach
Jack, Edward Douglas Bryant, Anthony Birch, Ronney B. Panerai, Dragana Nikolic, Diederik Bulters & David Simpson, 2021, Physiological Measurement, 42(10)
DOI: 10.1088/1361-6579/ac27b8
Type: article
The INfoMATAS project: methods for assessing cerebral autoregulation in stroke
David Simpson, Stephen J. Payne & Ronney B. Panerai, 2021, Journal of Cerebral Blood Flow and Metabolism
DOI: 10.1177/0271678X211029049
Type: review
A Data-Driven Approach to Transfer Function Analysis for Superior Discriminative Power: Optimized Assessment of Dynamic Cerebral Autoregulation
jia liu, Zhen-Ni Guo, David Simpson, Pandeng Zhang, Chang Liu, Jia-Ning song, xinyi Leng & Yi Yang, 2020, IEEE Journal of Biomedical and Health Informatics, 25(4), 909-921
DOI: 10.1109/JBHI.2020.3015907
Type: article
Changes in cerebral autoregulation and blood biomarkers after remote ischemic preconditioning
Zhen Ni Guo, Wei Tong Guo, Jia Liu, Junlei Chang, Hongyin Ma, Peng Zhang, Fu Liang Zhang, Ke Han, Han Hwa Hu, Hang Jin, Xin Sun, David Martin Simpson & Yi Yang, 2019, Neurology, 93(1), e8-e19
DOI: 10.1212/WNL.0000000000007732
Type: article
Spectral estimation of HRV in signals with gaps
L. Rodríguez-Liñares & D.M. Simpson, 2019, Biomedical Signal Processing and Control, 52, 187-197
DOI: 10.1016/j.bspc.2019.04.006
Type: article
Reproducibility of dynamic cerebral autoregulation parameters
Marit L. Sanders, Jurgen A.H.R. Claassen, Marcel Aries, Edson Bor-Seng-Shu, Alexander Caicedo, Max Chacon, Erik D. Gommer, Sabine Van Huffel, José L. Jara, Kyriaki Kostoglou, Adam Mahdi, Vasilis Z. Marmarelis, Georgios D. Mitsis, Martin Müller, Dragana Nikolic, Ricardo C. Nogueira, Stephen J. Payne, Corina Puppo, Dae C. Shin, David M. Simpson, Takashi Tarumi, Bernardo Yelicich, Rong Zhang, Ronney B. Panerai & Jan Willem J. Elting, 2018, Physiological Measurement, 39(12)
DOI: 10.1088/1361-6579/aae9fd
Type: article
CrossTalk opposing view
David Simpson & Jurgen Claassen, 2018, Journal of Physiology, 596(1), 7-9
DOI: 10.1113/JP273900
Type: article