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Ms. Himanshi Chawla BSc, MSc

Postgraduate Research Student in School of Biological Sciences

Ms. Himanshi Chawlais a postgraduate research student within biological sciences at the University of Southampton.

Ms. Himanshi Chawla joined Biological Sciences as a PhD student in Glycobiology Therapeutics Laboratory. She aims to study glycosylation of the viral glycoproteins such as Human Immunodeficiency viruses (HIV-1), severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).

2019-present. PhD in Biological Sciences, University of Southampton, UK.

2017-2019. MSc in Medical Biochemistry, All India Institute of Medical Sciences, India.

2014-2017. BSc in Microbiology, University of Delhi, India.

Research

Publications

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Research interests

Himanshi was investigating the isolation and characterization of antibodies against different subtypes of HIV-1 during her masters thesis. The HIV-1 glycoprotein is heavily glycosylated typically contains 50% of carbohydrates by mass, which protects the highly mutative surface from the immune system and constantly evolves to escape antibody recognition. Glycosylation is an important parameter in immunogen design, this prompted her to apply for PhD studies in Professor Max Crispin’s lab (Glycobiology therapeutics laboratory). The Crispin laboratory have developed a methodology to define the glycosylation of candidate immunogens and have determined glycan composition on both global and site-specific level of various viruses including HIV-1, Lassa virus, MERS, SARS-CoV-1, SARS-CoV-2. Himanshi is utilizing this method to elucidate the glycosylation of protein derived from nucleotide-based vaccines and to compare the glycosylation with the recombinant protein.

PhD Supervision

Professor Max Crispin

PhD title

Immunogen glycosylation in protein and nucleic-acid based delivery systems

PhD Funding

Consortium for HIV/AIDS vaccine development (CHAVD)

Research group

Molecular and Cellular Biosciences

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Articles

Ms. Himanshi Chawla
School of Biological Sciences
Faculty of Environmental and Life Sciences
Life Sciences Building 85
University of Southampton
Highfield Campus
Southampton
SO17 1BJ

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