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The University of Southampton
Biological SciencesPostgraduate study
Email:
j.fish@soton.ac.uk

Miss Johanna A Fish MChem

Postgraduate research student

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Johanna is a researcher, primarily within Chemistry, working on the biophysical properties of PROTACs for use in medicinal chemistry. Her interest in drug development has grown throughout her undergraduate studies, particularly for manipulation of protein-protein interactions, allowing ‘undruggable’ targets to become more easily accessible.

As such, the South Coast Biosciences Doctoral Training Programme (SoCoBio DTP) is the perfect opportunity to work at the interface between chemistry and biology, developing these skills for drug discovery.

2020-present: PhD Biological Sciences, University of Southampton, UK.

2016-2020: MChem (Hons) Chemistry, University of Southampton, UK.

Research interests

I am interested in the development of novel antibiotic and cancer therapeutics, using in silico studies before synthesis and in vitro analysis of these compounds, as well as biophysical analysis (DSF, NMR, ITC etc)

Masters dissertation: Investigating Clinical Cancer Therapeutics Conjugated with Spatially Biased DNA Nanopores

Summer project: Total synthesis of korormicin using natural product derivatives

Undergraduate Honours Dissertation: Synthesis of fluorinated motifs for logP measurement and application within medicinal chemistry

Research project: Dissecting signalling pathways using PROTAC chemical probes

Supervisors:

Dr Matthias Baud
Professor Bruno Linclau
Professor Giorgios Giamas (University of Sussex)

Funding: South Coast Biosciences Doctoral Training Programme (BBSRC funded)

Research group

Molecular and Cellular Biosciences

Wellbeing Champion, SoCoBio DTP

RSC member

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Article

Demonstrator: Chemistry Undergraduate Laboratory Practicals

Miss Johanna A Fish
School of Biological Sciences
Faculty of Environmental and Life Sciences
Life Sciences Building 85
University of Southampton
Highfield Campus
Southampton
SO17 1BJ

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