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The University of Southampton
Biological SciencesPostgraduate study
Phone:
07425131885
Email:
J.Haszczyn@soton.ac.uk

Miss Johanna Haszczyn BSc

Postgraduate research student

Miss Johanna Haszczyn's photo

Miss Johanna Haszczyn is a postgraduate research student within Biological Sciences, University of Southampton.

In 2020 Johanna finished her undergraduate degree in Pharmacology. It was during this time that she realised her affinity towards toxicology and neuroscience and was enveloped by the potential to research after completing her final year dissertation. These experiences cemented her decision to commence her own research, in particular with anticholinesterases.

BSc Pharmacology, University of Portsmouth, UK

Research interests

The inhibition of acetylcholinesterase by carbamates and organophosphates results in the continuous stimulation of nicotinic and muscarinic cholinergic receptors. This can be fatal due to the lack of recovery from the effects on the autonomic, neuromuscular and central neurotransmission. This form of acute poisoning has been seen in nerve agent attacks, such as in Salisbury and Tomsk, but is also prevalent in agricultural environments with the use of organophosphate pesticides. The treatments currently available have limitations, with no antidote readily available.

The project hopes to understand the mechanisms of this intoxication, and to identify novel routes of mitigation of the effects seen in anticholinesterase poisoning in the C. elegans model.

Research project: Investigations of the determinants of nerve agent potency to define novel routes to mitigate the effects of environmental toxins.

Supervisors:

Professor Vincent O’Connor
Professor Lindy Holden-Dye
Dr Chris Green
Dr James N Kearn
Dr John E Tattersall

Funding Agency:

Biotechnology and Biological Sciences Research Council
South Coast Biological Sciences Doctoral Training Programme
University of Southampton
Defence Science Technology Laboratory

Research group

Neuroscience

Affiliate research group

Southampton Neuroscience Group (SoNG)

Member of the British Pharmacological Society

Member of the British Neuroscience Association

Demonstrator in:

BIOL2048 Principles of Pharmacology

Miss Johanna Haszczyn
School of Biological Sciences
Faculty of Environmental and Life Sciences
Life Sciences Building 85
University of Southampton
Highfield Campus
Southampton
SO17 1BJ

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