Skip to main navigationSkip to main content
The University of Southampton
Biological Sciences

Research project: Structure and Function of Membrane Proteins

Currently Active: 
Yes

Although significant advances have been made in obtaining crystal structures of membrane proteins, very few membrane proteins have been crystallised. Even when proteins have been crystallised certain parts of the structure remain elusive.

It is therefore still necessary to continue using fluorescence and other indirect techniques to provide information about the structure of membrane proteins.

We are using molecular biology techniques to modify a range of membrane proteins including the potassium channels, mechanosensitive sensitive channels, calcium pumps and diacylglycerol kinase from bacterial sources to provide valuable information about structure and conformation.

Related research groups

Molecular and Cellular Biosciences
Share this research project Share this on Facebook Share this on Twitter Share this on Weibo
Privacy Settings