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The University of Southampton
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Professor Bruno J Linclau 

Professor of Organic Chemistry, Deputy Head of School Research and Enterprise

Professor Bruno J Linclau's photo

Professor Bruno Linclau was appointed into his current position in August 2015 as Professor of Organic Chemistry. He is Head of the Organic Chemistry: Synthesis, Catalysis and Flow Section.





Bruno Linclau graduated from the University of Ghent, Belgium in 1992. His undergraduate thesis was carried out at Leicester University as an ERASMUS exchange student with Dr P R Jenkins during his final year. Back in Ghent, he joined the group of Professor M Vandewalle for his PhD (1992 - 1996, funded by the Belgian "National Fund of Scientific Research"), where he completed the total synthesis of several Vitamin D analogues. This was followed by a postdoctoral stay with Professor D P Curran in Pittsburgh PA (USA) (1997 - 1999), with a fellowship from the "Belgian American Educational Foundation" and from the University of Pittsburgh. There he worked on fluorous chemistry applications in combinatorial chemistry and developed a fluorous scavenger approach illustrated with automated solution phase parallel synthesis of urea libraries. He joined the Chemistry at Southampton University as a lecturer in August 1999, followed by a promotion to Senior Lecturer in 2005, to Reader in 2013, and to Professor in 2015. He is Head of the Organic Chemistry Section.

He is a member of the Royal Society of Chemistry (RSC) Carbohydrate Subject Group Committee, and of the RSC Fluorine Subject Group Committee. He is also a regular member of the American Chemical Society (ACS), and of the Society of Chemistry and Industry (SCI).

Research interests

We are working in the field of synthetic organic chemistry. Projects often involve the development of new methodology with application in the total synthesis of natural products and analogues, or for the synthesis of compounds of biological interest. We are also interested in carbohydrate and organofluorine chemistry, and in the development of immobilised reagents for use in parallel synthesis.

Research group

Organic Chemistry: Synthesis, Catalysis and Flow

Research project(s)

Linclau: The Influence of Fluorination on Lipophilicity

Linclau:Intramolecular hydrogen bonding between organofluorine and alcohols

Linclau: Polyfluorinated Carbohydrates

Linclau: The influence of fluorination on hydrogen bonding properties of functional groups

Linclau: The synthesis of luminacin D


LabFact is a project that involves 6 institutes and one company within the FCE region (CNRS, ENSICAEN, Universities of Caen, Rouen, Sussex and Southampton and Pareon Chemicals), bringing together world experts in flow chemistry and reagentless synthesis. 

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Key Publications


Book Chapter

Creative Media and Artefacts



Professor Bruno J Linclau
Chemistry University of Southampton Highfield Southampton SO17 1BJ

Room Number: 30/3036

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