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The University of Southampton

BIOL2048 Principles of Pharmacology

Module Overview

Aims and Objectives

Learning Outcomes

Knowledge and Understanding

Having successfully completed this module, you will be able to demonstrate knowledge and understanding of:

  • Outline key principles pharmacogenomics to explain how the genome impacts the way in which drugs interact with biological systems
Subject Specific Intellectual and Research Skills

Having successfully completed this module you will be able to:

  • Extract primary data for description and discussion in the style of a scientific publication. Utilising observations made by drugs with distinct modes of action.
Learning Outcomes

Having successfully completed this module you will be able to:

  • Describe the basic mechanism of drug receptor interactions and the quantitative analysis of these interactions. This will include applying the law of mass action and drug receptor interactions and its use to obtain quantitative estimates of agonist and antagonists binding
  • Explain how drugs enter the body/tissues and some of the mechanisms responsible for their subsequent removal.
  • Describe the mechanisms of action of drugs with distinct mode of actions that modify autonomic nervous system.
  • Give examples of drugs that act on the neuromuscular junction and describe their mode of action.
  • Describe the ways in which selective drugs interact with the distinct classes of receptors mediating the action of the neurotransmitters histamine and 5-hydroxytryptamine


Pharmcodynamics Pharmacokinetics Receptor structure function Pharmacology interactions in key body systems.

Learning and Teaching

Teaching and learning methods

Lectures, lab based practicals, class and paper based calculations and scientific report writing.

Practical classes and workshops20
Independent Study60
Completion of assessment task15
Total study time150



Laboratory Assignment


MethodPercentage contribution
Final Exam  (2 hours) 75%
Scientific report  () 25%
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