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The University of Southampton

Research project: Characterisation and computational modelling of acrylic bone cement polymerisation

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Acrylic bone cements have been used as a method of fixation for over 50 years but despite improvements in cement handling techniques and numerous attempts to improve the mechanical properties of the cement in other ways, the cement is often highlighted as the weak link in the joint replacement system.

Aseptic loosening is cited as the cause for the majority of revision operations and cement degradation has been shown to be a contributor to the loosening process. In-vivo, cement is subject to cyclic loads and these are the primary cause of cement damage. Residual stresses generated during the polymerisation of the cement are now thought to play a significant role in cement failure. This PhD project examined the development of residual stresses as a result of thermal and chemical changes during polymerisation of the cement, using experimental testing to characterise the mechanical properties of cement during preparation and following polymerisation.

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Related research groups

Bioengineering Science
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