Skip to main navigationSkip to main content
The University of Southampton
Health SciencesOur research

Research project: FeeTURA4 / Forefoot complications in patients with rheumatoid arthritis: identification, impact and intervention

Currently Active: 
Yes

The FeeTURA study is now in its fourth phase of the programme of work. The aim of this phase is to investigate the epidemiology and pathology of forefoot complications in patients who have rheumatoid arthritis and who are starting biologic therapies.

This is a prospective cohort study designed to investigate the epidemiology and pathology of forefoot complications in patients who have rheumatoid arthritis (RA). Preliminary data suggest that FFB are highly prevalent in this patient population and that this pathology may be associated with both underlying disease pathology and mechanical dysfunction. A variety of outcomes are being used to investigate this, including ultrasound imaging, magnetic resonance imaging and histological analyses combined with Vicon motion analysis and interface foot pressures. FeeTURA has been supported by the Southampton Rheumatology Trust and an NIHR CATP Fellowship award. Unique data from this study suggests that there is negative association of forefoot synovitis and FFB in RA patients with peak plantar foot pressures and that both factors are highly variable over time. Through further funding from partnership with Solent NHS Podiatry via an NIHR Clinical Lectureship for Dr Lindsey Hooper the research will investigate underlying forefoot pathology following intervention with biologic therapies in other cohorts of patients who have RA. This will be important in determination of optimal interventions for foot pain.

Funder: National Institute for Health Research

Associated research themes

Rheumatoid arthritis

Ultrasound Imaging

Foot and ankle pathology

Forefoot bursitis

Joint synovitis

Related research groups

Active Living and Rehabilitation
Image one
Image two

Key Publications

Share this research project Share this on Facebook Share this on Twitter Share this on Weibo
Privacy Settings