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Research project

Boche - ARUK - Locus coeruleus: its role in cortical and subcortical inflammation in Alzheimer's disease

Staff

Lead researchers

Professor Delphine Boche

Professor of Neuroimmunopathology
Research interests
  • Neuroimmunology and neurodegeneration
  • Immunophenotyping immune cells
  • Human brain pathology
Connect with Delphine

Email: D.Boche@soton.ac.uk

Other researchers

Emeritus Professor Clive Holmes

Connect with Clive

Email: C.Holmes@soton.ac.uk

Research outputs

Changes in the locus Coeruleus during the course of Alzheimer’s disease and their relationship to cortical pathology
Rebecca Claire Beardmore, Matthew Durkin, Faizan Zayee-Mellick, Laurie C. Lau, James A.R. Nicoll, Clive Holmes & Delphine Boche, 2024, Neuropathology and Applied Neurobiology
Type: article
Neuropathology of the Locus Coeruleus in Alzheimer's disease
2022
Type: thesis
The locus coeruleus in aging and Alzheimer’s Disease: a postmortem and brain imaging review
Rebecca C Beardmore, Ruihua Hou, Angela Darekar, Clive Holmes & Delphine Boche, 2021, Journal of Alzheimer's Disease, 83(1), 5-22
DOI: 10.3233/JAD-210191
Type: review