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Research project

Boche - ARUK - Locus coeruleus: its role in cortical and subcortical inflammation in Alzheimer's disease


Lead researcher

Professor Delphine Boche

Professor of Neuroimmunopathology

Research interests

  • Delphine serves on a range of neuroscience research projects focusing on neuroinflammation and neurodegeneration.
  • Her main research interest is to develop a greater understanding of the role of neuroinflammation in relation with ageing, neurological diseases and systemic inflammation, using the approaches of human brain analysis. Her research focuses on microglia, the immune cells of the brain, where she has developed protocols to immunophenotype microglia in humans using markers relating to a specific function allowing us to investigate the role of these cells in different neurological conditions.
  • Her work is located at the junction between clinical neurodegenerative disease, human neuropathology and experimental neuroscience where she has developed an expertise in neuroimmunopathology
Other researchers

Collaborating research institutes, centres and groups

Research outputs

Rebecca Claire Beardmore
, 2022
Type: thesis
Rebecca C Beardmore,
Angela Darekar,
, 2021 , Journal of Alzheimer's Disease , 83 (1) , 5--22
Type: review
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