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Research project

MacArthur BB/L000512/1 Dissecting the molecular basis of cell-cell variability in mouse embryonic stem cell populations using system approaches

Staff

Lead researcher

Professor Benjamin Macarthur

Personal Chair

Research interests

  • Mathematical modeling
  • Machine learning 
  • Networks

Research outputs

Machine learning of stem cell identities from single-cell expression data via regulatory network archetypes
Patrick Stumpf,
& Benjamin Macarthur
, 2019 , Frontiers in Genetics , 10
DOI: 10.3389/fgene.2019.00002
Type: article
Stem cell differentiation as a non-Markov stochastic process
Patrick Stumpf,
Rosanna C.G. Smith,
Michael Lenz,
Andreas, A. Schuppert,
Franz-Josef Muller,
Ann Babtie,
Thalia E. Chan,
Michael P.H. Stumpf,
Colin P. Please,
Sam D. Howison,
Fumio Arai,
& Benjamin D. Macarthur
, 2017 , Cell Systems , 5 (3) , 268--282.e7
DOI: 10.1016/j.cels.2017.08.009
Type: article
Information-theoretic approaches to understanding stem cell variability
Rosanna Smith,
& Benjamin Macarthur
, 2017 , Current Stem Cell Reports , 3 (3) , 225--231
DOI: 10.1007/s40778-017-0093-5
Type: article
Nanog fluctuations in embryonic stem cells highlight the problem of measurement in cell biology
Rosanna Smith,
Patrick Stumpf,
Sonya Ridden,
Aaron Sim,
Sarah Filippi,
Heather Harrington,
& Benjamin Macarthur
, 2017 , Biophysical Journal , 112 (12) , 2641–2652
DOI: 10.1016/j.bpj.2017.05.005
Type: article
Noise-processing by signaling networks
Styliani Kontogeorgaki,
Ruben Sanchez Garcia,
Robert Ewing,
Konstantinos Zygalakis,
& Benjamin Macarthur
, 2017 , Scientific Reports , 7 (1)
DOI: 10.1038/s41598-017-00659-x
Type: article
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