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Research project

Microfluidic Deflection for High Throughput Single Platelet Sensitivity Testing

Project overview

BHF Grant Number: FS/13/67/30473


Lead researcher

Dr Jonathan West

Associate Professor

Research interests

  • Platelet Diversity The lab has a keen interest in understanding the nature and consequences of platelet functional diversity. Using a droplet microfluidics strategy we can measure intrinsic platelet behaviour. Broad-continuum sensitivity was identified, with hypersensitive platelets able to drive heterotypic system polarisation. Current research aims at characterising platelet dynamics and transcriptome remodelling in response to stimulation to pin-point sub-populations governing thrombosis.
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