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Research project

NeuroChip: A microfluidic sensor for electrophysiological recording of a nematode neural network - Holden Dye - BBSRC

Staff

Lead researcher

Professor Lindy Holden-Dye BSc, MSc, PhD, FRSB, FBPhS

PROFESSOR OF NEUROSCIENCES

Research interests

  • Neuropharmacology
  • Invertebrate neuroscience
  • Nematode neurobiology
Connect with Lindy

Email: L.M.Holden-Dye@soton.ac.uk

Other researchers

Professor Vincent O'connor

Professor of Neurochemistry

Research interests

  • Molecular mechanism of synaptic function and dysfunction
  • Synaptic degeneration
  • Genetic models of synaptic and neuronal dysfunction
Connect with Vincent

Email: V.M.OConnor@soton.ac.uk

Professor Hywel Morgan MBE

Professor of Bioelectronics

Research interests

  • Microfluidics
  • Bio-sensors
  • Lab-on-a-chip technologies
Connect with Hywel

Email: hm@ecs.soton.ac.uk

Collaborating research institutes, centres and groups

Digital Health and Biomedical Engineering

Our group brings together engineers and computer scientists to discover new approaches to diagnose and manage health and medical conditions.

Plants and Food Security

We study the response of plants to the environment at the molecular, whole plant and ecological levels. This includes interactions with nematodes, insects and microbes.

Research outputs

Neuroligin tuning of pharyngeal pumping reveals an extrapharyngeal modulation of Caenorhabditis elegans feeding
Fernando Calahorro, Francesca Keefe, James Dillon, Lindy Holden-dye & Vincent O'connor, 2019, The Journal of Experimental Biology, 222((Pt 3)), 1-11
DOI: 10.1242/jeb.189423
Type: article
Chemical activation of a food deprivation signal extends lifespan
Mark Lucanic, Theo Garrett, Ivan Yu, Fernando Calahorro Nunez, Azar Asadi Shahmirzadi, Aaron Miller, Matthew S. Gill, Robert E. Hughes, Linda Holden-Dye & Gordon J. Lithgow, 2016, Aging Cell, 15(5), 832-841
DOI: 10.1111/acel.12492
Type: article