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Research project

Next generation antibody-drug conjugates for cancer therapy

Staff

Lead researcher

Professor Diana Eccles

Dean of Medicine

Research interests

  • Genetic predispostion to cancer
  • Cancer susceptibility variant interpetation and clinical application

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Other researchers

Professor Stephen Beers

Professor of Immunology & Immunotherapy

Research interests

  • Edit
  • Antibody Effector Functions Monoclonal antibodies (mAb) have become established in the treatment of a variety of malignancies - transforming patient outcomes. Despite this undoubted impact, responses remain variable and their mechanisms of action and of tumour resistance are controversial. Our research is focussed on understanding these complex processes using a variety of complementary models and systems to better inform antibody selection, design and clinical application.

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Professor Peter Johnson CBE MD FRCP FMedSci

Professor of Medical Oncology

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Collaborating research institutes, centres and groups

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