Research project

Photo-Electro: Transforming Chemical Synthesis, Discovery and Manufacture

Research areas:

Chemistry
Research groups:

Organic Chemistry, Synthesis, Catalysis
Lead researcher:

Professor Richard Brown
Other researchers:

Professor David Harrowven
Research funder:

EPSRC
Status:

Active

Staff

Lead researcher

Professor Richard Brown

Professor of Organic Chemistry

Connect with Richard

Email: r.c.brown@soton.ac.uk

Other researchers

Professor David Harrowven

Professor of Chemistry

Connect with David

Email: dch2@soton.ac.uk

Collaborating research institutes, centres and groups

Organic Chemistry, Synthesis, Catalysis

We develop environmentally sustainable approaches to chemical manufacture that minimise chemical waste, improve product velocity and reduce the need to isolate intermediates.

Research outputs

Flow photochemical routes to indoles and 8-membered lactones, and their application in target synthesis

William Raimbach

, 2023

Type: thesis

High-productivity single-pass electrochemical birch reduction of Naphthalenes in a continuous flow electrochemical Taylor Vortex Reactor

Darren S. Lee,

Ashley Love,

Zakaria Mansouri,

Toby H. Waldron Clarke,

David C. Harrowven,

Richard Jefferson-Loveday,

Stephen J. Pickering,

Martyn Poliakoff,

& Michael W. George

, 2022 , Organic Process Research & Development , 26 (9) , 2674--2684

DOI: 10.1021/acs.oprd.2c00108

Type: article

A flow electrochemistry-enabled synthesis of 2-substituted N-(methyl-d)piperidines

Azzam A.M. Hadedi,

Stuart Sawyer,

Stuart J. Elliott,

Robert A Green,

Daniel J. O’leary,

Richard C.D. Brown,

& Lynda J. Brown

, 2022 , Journal of Labelled Compounds and Radiopharmaceuticals , 65 (14) , 361--368

DOI: 10.1002/jlcr.4006

Type: article

First example of organocatalysis by cathodic N-heterocyclic carbene generation and accumulation using a divided electrochemical flow cell

Daniele Rocco,

Ana Folgueiras Amador,

Richard C.D. Brown,

& Marta Feroci

, 2022 , Beilstein Journal of Organic Chemistry , 18 , 979--990

DOI: 10.3762/bjoc.18.98

Type: article

Cathodic radical cyclisation of aryl halides using a strongly-reducing catalytic mediator in flow

Ana Folgueiras Amador,

Alexander Teuten,

Mateo Salam Perez,

James Pearce,

Guy Denuault,

Derek Pletcher,

Phillip James Parsons,

David C. Harrowven,

& Richard C.D. Brown

, 2022 , Angewandte Chemie International Edition , 61 (35)

DOI: 10.1002/anie.202203694

Type: article