Project overview
Autophagy, a key survival mechanism allowing cells to tolerate stress or lack of nutrients, promotes tumourigenesis, in particular in RAS-mutated cancer. We demonstrated that elevated autophagy activity bypasses oncogenic RAS-induced senescence in order to support tumour growth (PNAS 2012). This project aims to comprehensively study the role of autophagy in oncogenic RAS-induced tumour invasion.
Staff
Lead researcher
